Age at natural menopause and its associated characteristics among Brazilian women: cross-sectional results from ELSI-Brazil.

Autor:	Ygnatios NTM, Mambrini JVM, Torres JL, Detomi LMD; From the Santa Rita University Center (UNIFASAR), Conselheiro Lafaiete, Minas Gerais, Brazil., Braga LS, Lima-Costa MF, Moreira BS; Center for Studies in Public Health and Aging (NESPE) of the Oswaldo Cruz Foundation (FIOCRUZ) and the Federal University of Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil.
Jazyk:	angličtina
Zdroj:	Menopause (New York, N.Y.) [Menopause] 2024 Aug 01; Vol. 31 (8), pp. 693-701. Date of Electronic Publication: 2024 Jul 02.
DOI:	10.1097/GME.0000000000002385
Abstrakt:	Objectives: This study aimed to determine the median age at natural menopause and analyze lifestyle, anthropometric, and dietary characteristics associated with the age at natural menopause among Brazilian women. Methods: This cross-sectional study involved 2,731 women 50 years and over, drawn from the baseline of the Brazilian Longitudinal Study of Aging (ELSI-Brazil, 2015/16). Nonparametric Kaplan-Meier cumulative survivorship estimates were used to assess the median timing of natural menopause. Cox proportional hazards regression models were employed to estimate the associations between age at natural menopause and exposure variables. Results: The overall median age at natural menopause was 50 years. In the adjusted Cox model, current smoking (hazard ratio [HR], 1.11; 95% CI, 1.01-1.23) and underweight (HR, 1.34; 95% CI, 1.12-1.61) were associated with earlier natural menopause. Conversely, performing recommended levels of physical activity in the last week (HR, 0.88; 95% CI, 0.80-0.97), being overweight (HR 0.86; 95% CI, 0.74-0.99), and adhering to two or three healthy eating markers (HR, 0.80; 95% CI, 0.66-0.97; HR, 0.76; 95% CI, 0.61-0.94, respectively) were associated with later age at natural menopause. Binge drinking and waist circumference were not associated with age at natural menopause. Conclusions: Lifestyle, anthropometric, and dietary characteristics are significant factors that affect the age at natural menopause. Our findings can contribute to public policies targeted at Brazilian women's health. Competing Interests: Financial disclosure/conflicts of interest: None reported. (Copyright © 2024 by The Menopause Society.)
Databáze:	MEDLINE
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