Relationship between COVID-19 and orofacial clefts.

Autor:	Molnárová A; Department of Plastic Surgery, Faculty of Medicine, Comenius University in Bratislava, Hospital Ružinov, Bratislava, Slovakia., Fekiačová D; Department of Plastic Surgery, Faculty of Medicine, Comenius University in Bratislava, Hospital Ružinov, Bratislava, Slovakia., Záhumenský J; Department of Gynecology and Obstetrics, Faculty of Medicine, Comenius University Bratislava, Hospital Ružinov, Bratislava, Slovakia., Rosoľanková M; Department of Gynecology and Obstetrics, Faculty of Medicine, Comenius University Bratislava, Hospital Ružinov, Bratislava, Slovakia., Ujházy E; Centre of Experimental Medicine of the Slovak Academy of Sciences, Institute of Experimental Pharmacology and Toxicology, Bratislava, Slovakia., Dubovický M; Centre of Experimental Medicine of the Slovak Academy of Sciences, Institute of Experimental Pharmacology and Toxicology, Bratislava, Slovakia., Palenčár D; Department of Plastic Surgery, Faculty of Medicine, Comenius University in Bratislava, Hospital Ružinov, Bratislava, Slovakia.
Jazyk:	angličtina
Zdroj:	General physiology and biophysics [Gen Physiol Biophys] 2024 Jul; Vol. 43 (4), pp. 313-319.
DOI:	10.4149/gpb_2024012
Abstrakt:	The work presents the connection between the infection of COVID-19 during pregnancy and non-syndromic orofacial clefts (NSOFC). Aim of the study was to compare the incidence of COVID-19 disease during mother´s pregnancy between a group of the children with NSOFC and a control group of the children without NSOFC. COVID-19 was confirmed by polymerase chain reaction (PCR) test. The study showed significantly higher incidence of COVID-19 disease in the group of mothers who gave birth to a child with NSOFC in comparison to the group of mothers who gave birth to a child without NSOFC. Our results indicate the possible participation of the infection of COVID-19 in the formation of NSOFCs.
Databáze:	MEDLINE
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