Epidemiology of travel-associated dengue from 2007 to 2022: A GeoSentinel analysis.

Autor:	Duvignaud A; Department of Infectious Diseases and Tropical Medicine, Division of Tropical Medicine and Clinical International Health, Hôpital Pellegrin, CHU Bordeaux, Bordeaux, France.; Global Health in the Global South - University of Bordeaux, National Institute for Health and Medical Research (INSERM) UMR 1219 - Research Institute for Sustainable Development (IRD) EMR 271, Bordeaux Population Health Research Centre, Bordeaux, France., Stoney RJ; Division of Global Migration Health, Centers for Disease Control and Prevention, Atlanta, GA, USA., Angelo KM; Division of Global Migration Health, Centers for Disease Control and Prevention, Atlanta, GA, USA., Chen LH; Division of Infectious Diseases and Travel Medicine, Mount Auburn Hospital, Cambridge, MA, USA.; Faculty of Medicine, Harvard Medical School, Boston, MA, USA., Cattaneo P; Department of Infectious Tropical Diseases and Microbiology, IRCCS Sacro Cuore-Don Calabria Hospital, Negrar di Valpolicella, Verona, Italy., Motta L; Department of Infectious Tropical Diseases and Microbiology, IRCCS Sacro Cuore-Don Calabria Hospital, Negrar di Valpolicella, Verona, Italy., Gobbi FG; Department of Infectious Tropical Diseases and Microbiology, IRCCS Sacro Cuore-Don Calabria Hospital, Negrar di Valpolicella, Verona, Italy.; Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy., Bottieau E; Department of Clinical Sciences, Institute of Tropical Medicine, 155 Nationalestraat, Antwerp 2000, Belgium., Bourque DL; Section of Infectious Diseases, Department of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA., Popescu CP; Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.; Dr Victor Babeș Clinical Hospital and Infectious Diseases, Bucharest, Romania., Glans H; Department of Infectious Diseases, Karolinska University Hospital, Stockholm, Sweden.; Department of Medicine Huddinge, Division of Infectious Diseases, Karolinska Institutet, Stockholm, Sweden., Asgeirsson H; Department of Infectious Diseases, Karolinska University Hospital, Stockholm, Sweden.; Department of Medicine Huddinge, Division of Infectious Diseases, Karolinska Institutet, Stockholm, Sweden., Oliveira-Souto I; Vall d'Hebron-Drassanes International Health Unit, Infectious Diseases Department, Vall d'Hebron University Hospital, International Health Programme of Catalan Health Institute (PROSICS), Barcelona, Spain.; Centres, Services and Reference Units (CSUR) Imported Tropical Diseases, Barcelona, Spain.; Centre for Biomedical Research Network on Infectious Diseases, Madrid, Spain., Vaughan SD; Department of Medicine, Division of Infectious Diseases, University of Calgary, Calgary, AB, Canada., Amatya B; CIWEC Hospital and Travel Medicine Center, Lainchaur, Kathmandu, Nepal., Norman FF; National Referral Unit for Tropical Diseases, Infectious Diseases Department, Ramón y Cajal University Hospital, CIBERINFEC, IRYCIS, Madrid, Spain.; Universidad de Alcalá, Madrid, Spain., Waggoner J; Department of Medicine, Division of Infectious Diseases, Emory University School of Medicine, Atlanta, GA, USA., Díaz-Menéndez M; Tropical Medicine Department, Hospital Universitario La Paz-Carlos III, IdIPAz, and CIBERINFECT, Madrid, Spain., Beadsworth M; Tropical and Infectious Disease Unit, Royal Liverpool University Hospital, Liverpool University Hospitals Foundation Trust, Liverpool, UK., Odolini S; University Division of Infectious and Tropical Diseases, University of Brescia and ASST Spedali Civili Hospital, Brescia, Italy., Camprubí-Ferrer D; ISGlobal, Hospital Clínic, Universitat de Barcelona, Barcelona, Spain., Epelboin L; Infectious and Tropical Diseases Unit and CIC Inserm 1424, Centre Hospitalier de Cayenne, Cayenne, French Guiana., Connor BA; Weill Cornell Medical College and the New York Center for Travel and Tropical Medicine, New York, NY, USA., Eperon G; Division of Tropical and Humanitarian Medicine, Geneva University Hospitals & Faculty of Medicine, University of Geneva, Geneva, Switzerland., Schwartz E; The Center of Geographical Medicine and Tropical Diseases, Sheba Medical Center, Tel HaShomer, Ramat Gan, Israel.; The Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel., Libman M; Department of Medicine, Division of Infectious Diseases, McGill University Health Centre, Montréal, Québec, Canada.; J.D. MacLean Centre for Tropical Diseases at McGill University, Montréal, Québec, Canada., Malvy D; Department of Infectious Diseases and Tropical Medicine, Division of Tropical Medicine and Clinical International Health, Hôpital Pellegrin, CHU Bordeaux, Bordeaux, France.; Global Health in the Global South - University of Bordeaux, National Institute for Health and Medical Research (INSERM) UMR 1219 - Research Institute for Sustainable Development (IRD) EMR 271, Bordeaux Population Health Research Centre, Bordeaux, France., Hamer DH; Department of Global Health, Boston University School of Public Health, Boston, MA, USA.; Center for Emerging Infectious Disease Policy and Research, Boston University, Boston, MA, USA.; National Emerging Infectious Disease Laboratory, Boston, MA, USA., Huits R; Department of Infectious Tropical Diseases and Microbiology, IRCCS Sacro Cuore-Don Calabria Hospital, Negrar di Valpolicella, Verona, Italy.
Jazyk:	angličtina
Zdroj:	Journal of travel medicine [J Travel Med] 2024 Oct 19; Vol. 31 (7).
DOI:	10.1093/jtm/taae089
Abstrakt:	Background: Dengue is a leading cause of febrile illness among international travellers. We aimed to describe the epidemiology and clinical characteristics of imported dengue in returning travellers evaluated at GeoSentinel sites from 2007 to 2022. Methods: We retrieved GeoSentinel records of dengue among travellers residing in non-endemic countries. We considered dengue confirmed when diagnosed by a positive dengue virus (DENV)-specific reverse-transcriptase polymerase chain reaction, positive NS-1 antigen and/or anti-DENV IgG seroconversion, and probable when diagnosed by single anti-DENV IgM or high-titre anti-DENV IgG detection. Severe dengue was defined as evidence of clinically significant plasma leakage or bleeding, organ failure, or shock, according to the 2009 World Health Organization guidance. Complicated dengue was defined as either severe dengue or dengue with presence of any warning sign. Analyses were descriptive. Results: This analysis included 5958 travellers with confirmed (n = 4859; 81.6%) or probable (n = 1099; 18.4%) dengue. The median age was 33 years (range: <1-91); 3007 (50.5%) travellers were female. The median travel duration was 21 days (interquartile range [IQR]: 15-32). The median time between illness onset and GeoSentinel site visit was 7 days (IQR: 4-15). The most frequent reasons for travel were tourism (67.3%), visiting friends or relatives (12.2%) and business (11.0%). The most frequent regions of acquisition were South East Asia (50.4%), South Central Asia (14.9%), the Caribbean (10.9%) and South America (9.2%). Ninety-five (1.6%) travellers had complicated dengue, of whom 27 (0.5%) had severe dengue and one died. Of 2710 travellers with data available, 724 (26.7%) were hospitalized. The largest number of cases (n = 835) was reported in 2019. Conclusions: A broad range of international travellers should be aware of the risk of acquiring dengue and receive appropriate pre-travel counselling regarding preventive measures. Prospective cohort studies are needed to further elucidate dengue risk by destination and over time, as well as severe outcomes and prolonged morbidity (long dengue) due to travel-related dengue. (Published by Oxford University Press on behalf of International Society of Travel Medicine 2024.)
Databáze:	MEDLINE
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