Late 68 Ga PSMA-positive Pancreatic Metastasis From Renal Cell Carcinoma in a Patient with Metastatic Prostate Cancer: A Mission Impossible.
| Autor: | Mateva G; Acibadem City Clinic UMBAL Mladost Hospital, Department of Nuclear Medicine, Sofia, Bulgaria., Novoselska N; Acibadem City Clinic UMBAL Mladost Hospital, Department of Nuclear Medicine, Sofia, Bulgaria., Dudov A; Acibadem City Clinic UMBAL Mladost Hospital, Department of Medical Oncology, Sofia, Bulgaria., Garcheva-Tsacheva M; Acibadem City Clinic UMBAL Mladost Hospital, Department of Nuclear Medicine, Sofia, Bulgaria., Bochev P; Acibadem City Clinic UMBAL Mladost Hospital, Department of Nuclear Medicine, Sofia, Bulgaria. |
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| Jazyk: | angličtina |
| Zdroj: | Molecular imaging and radionuclide therapy [Mol Imaging Radionucl Ther] 2024 Jun 28; Vol. 33 (2), pp. 112-114. |
| DOI: | 10.4274/mirt.galenos.2023.90582 |
| Abstrakt: | We present the case of a patient with newly diagnosed high-risk prostate cancer. The patient underwent nephrectomy for renal cell carcinoma (RCC) in 2009. The prostate-specific membrane antigen (PSMA) scan revealed a primary tumor with seminal vessel involvement, PSMA-positive regional lymph nodes, several nodular lung lesions with mild PSMA uptake, PSMA-positive mediastinal lymph nodes, and a PSMA-positive mass in the pancreatic head. Ultrasound-guided biopsy was performed for the pancreatic lesions revealing metastasis from a RCC. Simultaneous treatment for prostate cancer and metastatic RCC was initiated. To separate metastatic sites for both primaries, we attempted to use fluorodeoxyglucose positron emission tomography/computed tomography, which was moderately positive for the pancreatic mass but not for the other locations. RCC is a 68 Ga PSMA-positive tumor; the synchronous combination of RCC with prostate cancer can be confusing and requires more complex clinical interpretation. Competing Interests: Conflict of Interest: No conflicts of interest were declared by the authors. (Copyright© 2024 The Author. Published by Galenos Publishing House on behalf of the Turkish Society of Nuclear Medicine.) |
| Databáze: | MEDLINE |
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