Chronic lymphocytic leukemia patients with chromosome 6q deletion as the sole cytogenetic abnormality display a high frequency of RPS15 mutations and have a poor prognosis.

Autor: Pérez Carretero C; University of Salamanca, IBSAL, IBMCC, CSIC, Cancer Research Center, Salamanca, Spain.; Department of Hematology, University Hospital of Salamanca, Salamanca, Spain., González T; University of Salamanca, IBSAL, IBMCC, CSIC, Cancer Research Center, Salamanca, Spain.; Department of Hematology, University Hospital of Salamanca, Salamanca, Spain., Quijada Álamo M; University of Salamanca, IBSAL, IBMCC, CSIC, Cancer Research Center, Salamanca, Spain.; Department of Hematology, University Hospital of Salamanca, Salamanca, Spain., Rigolin GM; Hematology Section, St. Anna University Hospital, Ferrara, Italy., Dubuc A; Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts, USA., Villaverde Ramiro Á; University of Salamanca, IBSAL, IBMCC, CSIC, Cancer Research Center, Salamanca, Spain.; Department of Hematology, University Hospital of Salamanca, Salamanca, Spain., Rodríguez-Sánchez A; University of Salamanca, IBSAL, IBMCC, CSIC, Cancer Research Center, Salamanca, Spain.; Department of Hematology, University Hospital of Salamanca, Salamanca, Spain., Rubio A; Department of Hematology, Hospital Miguel Servet, Zaragoza, Spain., Dávila J; Department of Hematology, Hospital Nuestra Señora de Sonsoles, Ávila, Spain., Vidal MJ; Department of Hematology, Hospital Universitario, León, Spain., González Gascón Y Marín I; Department of Hematology, Hospital Universitario Infanta Leonor. Universidad Complutense, Madrid, Spain., Hernández-Rivas JÁ; Department of Hematology, Hospital Universitario Infanta Leonor. Universidad Complutense, Madrid, Spain., Benito R; University of Salamanca, IBSAL, IBMCC, CSIC, Cancer Research Center, Salamanca, Spain.; Department of Hematology, University Hospital of Salamanca, Salamanca, Spain., Volpe V; Dana Farber Cancer Institute, Boston, Massachusetts, USA., Davids MS; Dana Farber Cancer Institute, Boston, Massachusetts, USA., Abramson JS; Massachusetts General Hospital, Boston, Massachusetts, USA., Cuneo A; Hematology Section, St. Anna University Hospital, Ferrara, Italy., Dal Cin P; Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts, USA., Rodríguez-Vicente AE; University of Salamanca, IBSAL, IBMCC, CSIC, Cancer Research Center, Salamanca, Spain.; Department of Hematology, University Hospital of Salamanca, Salamanca, Spain.; Department of Human Anatomy and Histology, Faculty of Medicine, University of Salamanca, Salamanca, Spain., Hernández-Rivas JM; University of Salamanca, IBSAL, IBMCC, CSIC, Cancer Research Center, Salamanca, Spain.; Department of Hematology, University Hospital of Salamanca, Salamanca, Spain.
Jazyk: angličtina
Zdroj: American journal of hematology [Am J Hematol] 2024 Sep; Vol. 99 (9), pp. 1845-1848. Date of Electronic Publication: 2024 Jul 01.
DOI: 10.1002/ajh.27421
Databáze: MEDLINE