Effect of a 4-Week Telerehabilitation Program for People with Post-COVID Syndrome on Physical Function and Symptoms: Protocol for a Randomized Controlled Trial.

Autor:	Reeves JM; Physiotherapy Department, Royal Prince Alfred Hospital, Sydney, NSW, Australia.; Sydney School of Health Sciences, Faculty of Medicine and Health, the University of Sydney, Sydney, NSW, Australia., Spencer LM; Physiotherapy Department, Royal Prince Alfred Hospital, Sydney, NSW, Australia.; Sydney School of Health Sciences, Faculty of Medicine and Health, the University of Sydney, Sydney, NSW, Australia., Tsai LL; Physiotherapy Department, Royal Prince Alfred Hospital, Sydney, NSW, Australia.; Sydney School of Health Sciences, Faculty of Medicine and Health, the University of Sydney, Sydney, NSW, Australia., Baillie AJ; Sydney School of Health Sciences, Faculty of Medicine and Health, the University of Sydney, Sydney, NSW, Australia.; Allied Health, Sydney Local Health District, Sydney, NSW, Australia., Han Y; Physiotherapy Department, Canterbury Hospital, Sydney, NSW, Australia., Leung RWM; Physiotherapy Department, Concord Repatriation General Hospital, Sydney, NSW, Australia.; Respiratory Medicine, Concord Repatriation General Hospital, Sydney, NSW, Australia., Bishop JA; Physiotherapy Department, Balmain Hospital, Sydney, NSW, Australia., Troy LK; Department of Respiratory and Sleep Medicine, Royal Prince Alfred Hospital, Sydney, NSW, Australia.; Sydney Medical School, Faculty of Medicine and Health, the University of Sydney, Sydney, NSW, Australia., Corte TJ; Department of Respiratory and Sleep Medicine, Royal Prince Alfred Hospital, Sydney, NSW, Australia.; Sydney Medical School, Faculty of Medicine and Health, the University of Sydney, Sydney, NSW, Australia., Teoh AKY; Department of Respiratory and Sleep Medicine, Royal Prince Alfred Hospital, Sydney, NSW, Australia.; Sydney Medical School, Faculty of Medicine and Health, the University of Sydney, Sydney, NSW, Australia., Peters M; Respiratory Medicine, Concord Repatriation General Hospital, Sydney, NSW, Australia.; Sydney Medical School, Faculty of Medicine and Health, the University of Sydney, Sydney, NSW, Australia., Barton C; Department of Respiratory and Sleep Medicine, Royal Prince Alfred Hospital, Sydney, NSW, Australia., Jones L; Department of Respiratory and Sleep Medicine, Royal Prince Alfred Hospital, Sydney, NSW, Australia., Alison JA; Sydney School of Health Sciences, Faculty of Medicine and Health, the University of Sydney, Sydney, NSW, Australia.; Allied Health, Sydney Local Health District, Sydney, NSW, Australia.
Jazyk:	angličtina
Zdroj:	Physical therapy [Phys Ther] 2024 Jun 29. Date of Electronic Publication: 2024 Jun 29.
DOI:	10.1093/ptj/pzae080
Abstrakt:	Objective: COVID-19 has led to significant morbidity and mortality globally. Post-COVID sequelae can persist beyond the acute and subacute phases of infection, often termed Post-COVID Syndrome (PCS). There is limited evidence on the appropriate rehabilitation for people with PCS. The aim of this study is to evaluate the effect on exercise capacity, symptoms, cognition, anxiety, depression, health-related quality of life (HRQoL), and fatigue, of a 4-week, twice-weekly supervised pulmonary telerehabilitation program compared to usual medical care for people with PCS with persistent respiratory symptoms. Methods: The study will be a multi-site randomized controlled trial (RCT) with assessor blinding. Participants with confirmed previous COVID-19 infection and persistent respiratory symptoms who attend a post-COVID respiratory clinic will be randomized 1:1 to either an intervention group (IG) of 4 weeks, twice-weekly pulmonary telerehabilitation or a control group (CG) of usual medical care. Participants in the CG will be invited to cross-over into the IG after the week 4 assessment. Primary outcome: exercise capacity measured by the 1-minute sit-to-stand test. Secondary outcomes: 5 repetition sit-to-stand test; Montreal Cognitive Assessment; COVID-19 Yorkshire Rehabilitation Scale; COPD Assessment Test; 36-Item Short-Form Health Survey; Hospital Anxiety and Depression Scale; Fatigue Severity Scale; and the Kessler Psychological Distress Scale. Outcomes will be collected at baseline, after 4-weeks intervention or control period, after intervention in the cross-over group, and at 12-month follow-up. Impact Statement: Research into effective rehabilitation programs is crucial given the substantial morbidity associated with PCS and the lack of long-term data for COVID-19 recovery. A short duration pulmonary telerehabilitation program, if effective compared to usual care, could inform practice guidelines and direct future clinical trials for the benefit of individuals with persistent respiratory symptoms post-COVID. (© The Author(s) 2024. Published by Oxford University Press on behalf of the American Physical Therapy Association.)
Databáze:	MEDLINE
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