Racial/ethnic disparities in chronic wounds: Perspectives on linking upstream factors to health outcomes.

Autor: Cavalcante-Silva J; Department of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, Illinois, USA.; Center for Wound Healing and Tissue Regeneration, University of Illinois at Chicago, Chicago, Illinois, USA., Fantuzzi G; Department of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, Illinois, USA., Minshall R; Department of Anesthesiology, University of Illinois at Chicago, Chicago, Illinois, USA.; Department of Pharmacology, University of Illinois at Chicago, Chicago, Illinois, USA., Wu S; Department of Podiatric Medicine & Surgery, Center for Stem Cell and Regenerative Medicine, Rosalind Franklin University, Chicago, Illinois, USA., Oddo VM; Department of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, Illinois, USA., Koh TJ; Department of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, Illinois, USA.; Center for Wound Healing and Tissue Regeneration, University of Illinois at Chicago, Chicago, Illinois, USA.
Jazyk: angličtina
Zdroj: Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society [Wound Repair Regen] 2024 Sep-Oct; Vol. 32 (5), pp. 770-779. Date of Electronic Publication: 2024 Jun 29.
DOI: 10.1111/wrr.13200
Abstrakt: This review explores the complex relationship between social determinants of health and the biology of chronic wounds associated with diabetes mellitus, with an emphasis on racial/ethnic disparities. Chronic wounds pose significant healthcare challenges, often leading to severe complications for millions of people in the United States, and disproportionally affect African American, Hispanic, and Native American individuals. Social determinants of health, including economic stability, access to healthcare, education, and environmental conditions, likely influence stress, weathering, and nutrition, collectively shaping vulnerability to chronic diseases, such as obesity and DM, and an elevated risk of chronic wounds and subsequent lower extremity amputations. Here, we review these issues and discuss the urgent need for further research focusing on understanding the mechanisms underlying racial/ethnic disparities in chronic wounds, particularly social deprivation, weathering, and nutrition, to inform interventions to address these disparities.
(© 2024 The Author(s). Wound Repair and Regeneration published by Wiley Periodicals LLC on behalf of The Wound Healing Society.)
Databáze: MEDLINE
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