Association between the red cell distribution width and mortality in elderly patients with non-traumatic coma: An observational cohort study.

Autor:	Kim D; Department of Emergency Medicine, Chonnam National University Hospital, Gwangju, Republic of Korea., Lee D; Department of Emergency Medicine, Chonnam National University Hospital, Gwangju, Republic of Korea.; Department of Emergency Medicine, Chonnam National University Medical School, Gwangju, Republic of Korea., Lee J; Department of Emergency Medicine, Chonnam National University Hospital, Gwangju, Republic of Korea., Lee B; Department of Emergency Medicine, Chonnam National University Hospital, Gwangju, Republic of Korea.; Department of Emergency Medicine, Chonnam National University Medical School, Gwangju, Republic of Korea., Ko SW; Department of Emergency Medicine, Chonnam National University Hospital, Gwangju, Republic of Korea.
Jazyk:	angličtina
Zdroj:	Medicine [Medicine (Baltimore)] 2024 Jun 28; Vol. 103 (26), pp. e38773.
DOI:	10.1097/MD.0000000000038773
Abstrakt:	Elevated red blood cell distribution width (RDW) can be associated with disease severity. However, studies on RDW for the prognosis of elderly patients with non-traumatic coma (NTC) are lacking. This study aims to examine the relationship between RDW and outcomes in elderly patients with NTC. This observational cohort study included elderly patients (aged ≥ 65 years) with NTC between January 2022 and December 2022. We measured RDW upon patient arrival at the emergency department (ED). We conducted a multivariable analysis using logistic regression of relevant covariates to predict in-hospital mortality. Survival curves based on 30-day mortality were designed using the Kaplan-Meier method. The primary outcome was in-hospital mortality, and the secondary outcome was 30-day mortality. A total of 689 patients were included in the study, and in-hospital mortality was 29.6% (n = 204). Our results found that the RDWs of non-survivors were significantly greater than those of survivors (14.6% vs 13.6%). Multivariable analysis showed that RDWs at ED arrival were independently associated with in-hospital mortality (odds ratio, 1.126; 95% confidence interval, 1.047-1.212; P < .001). The Kaplan-Meier curve indicated that the survival probability of patients with a low RDW was greater than those with a high RDW. Having a high RDW at ED arrival was associated with in-hospital mortality in elderly patients with NTC. Competing Interests: The authors have no conflicts of interest to disclose. (Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.)
Databáze:	MEDLINE
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