Rapid Adaptation and Interspecific Introgression in the North American Crop Pest Helicoverpa zea.

Autor:	North HL; Department of Zoology, University of Cambridge, Cambridge CB2 3EJ, UK., Fu Z; Department of Entomology, Texas A&M University, College Station, TX 77843, USA.; Bioinformatics and Biostatistics Core, Van Andel Institute, Grand Rapids, MI 49503, USA., Metz R; AgriLife Genomics and Bioinformatics Service, Texas A&M University, College Station, TX 77843, USA., Stull MA; AgriLife Genomics and Bioinformatics Service, Texas A&M University, College Station, TX 77843, USA., Johnson CD; AgriLife Genomics and Bioinformatics Service, Texas A&M University, College Station, TX 77843, USA., Shirley X; Animal and Plant Health Inspection Service, United States Department of Agriculture, College Station, TX, USA., Crumley K; Agrilife Extension, Texas A&M University, Wharton, TX, USA., Reisig D; Department of Entomology and Plant Pathology, North Carolina State University, Plymouth, NC, 27962, USA., Kerns DL; Department of Entomology, Texas A&M University, College Station, TX 77843, USA., Gilligan T; Animal and Plant Health Inspection Service, United States Department of Agriculture, Fort Collins, CO, USA., Walsh T; Black Mountain Laboratories, Commonwealth Scientific and Industrial Research Organization, Canberra, Australia., Jiggins CD; Department of Zoology, University of Cambridge, Cambridge CB2 3EJ, UK., Sword GA; Department of Entomology, Texas A&M University, College Station, TX 77843, USA.
Jazyk:	angličtina
Zdroj:	Molecular biology and evolution [Mol Biol Evol] 2024 Jul 03; Vol. 41 (7).
DOI:	10.1093/molbev/msae129
Abstrakt:	Insect crop pests threaten global food security. This threat is amplified through the spread of nonnative species and through adaptation of native pests to control measures. Adaptations such as pesticide resistance can result from selection on variation within a population, or through gene flow from another population. We investigate these processes in an economically important noctuid crop pest, Helicoverpa zea, which has evolved resistance to a wide range of pesticides. Its sister species Helicoverpa armigera, first detected as an invasive species in Brazil in 2013, introduced the pyrethroid-resistance gene CYP337B3 to South American H. zea via adaptive introgression. To understand whether this could contribute to pesticide resistance in North America, we sequenced 237 H. zea genomes across 10 sample sites. We report H. armigera introgression into the North American H. zea population. Two individuals sampled in Texas in 2019 carry H. armigera haplotypes in a 4 Mbp region containing CYP337B3. Next, we identify signatures of selection in the panmictic population of nonadmixed H. zea, identifying a selective sweep at a second cytochrome P450 gene: CYP333B3. We estimate that its derived allele conferred a ∼5% fitness advantage and show that this estimate explains independently observed rare nonsynonymous CYP333B3 mutations approaching fixation over a ∼20-year period. We also detect putative signatures of selection at a kinesin gene associated with Bt resistance. Overall, we document two mechanisms of rapid adaptation: the introduction of fitness-enhancing alleles through interspecific introgression, and selection on intraspecific variation. Competing Interests: Conflict of Interest The authors declare no conflict of interest. (© The Author(s) 2024. Published by Oxford University Press on behalf of Society for Molecular Biology and Evolution.)
Databáze:	MEDLINE
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