Dispersal history of SARS-CoV-2 in Galicia, Spain.

Autor:	Gallego-García P; CINBIO, Universidade de Vigo, Vigo, Spain.; Galicia Sur Health Research Institute (IIS Galicia Sur), SERGAS-UVIGO, Vigo, Spain., Estévez-Gómez N; CINBIO, Universidade de Vigo, Vigo, Spain.; Galicia Sur Health Research Institute (IIS Galicia Sur), SERGAS-UVIGO, Vigo, Spain., De Chiara L; CINBIO, Universidade de Vigo, Vigo, Spain.; Galicia Sur Health Research Institute (IIS Galicia Sur), SERGAS-UVIGO, Vigo, Spain.; Department of Biochemistry, Genetics, and Immunology, Universidade de Vigo, Vigo, Spain., Alvariño P; CINBIO, Universidade de Vigo, Vigo, Spain., Juiz-González PM; Servicio de Microbiología del Complejo Hospitalario Universitario de Ferrol, Ferrol, Spain., Torres-Beceiro I; Servicio de Microbiología del Complejo Hospitalario Universitario de Ferrol, Ferrol, Spain., Poza M; Microbiology Research Group, Institute of Biomedical Research (INIBIC) - Interdisciplinary Center for Chemistry and Biology (CICA), University of A Coruña (UDC) - CIBER de Enfermedades Infecciosas (CIBERINFEC-ISCIII), Edificio Sur, Hospital Universitario A Coruña, As Xubias, A Coruña, Spain.; Microbiome and Health Group, Faculty of Sciences, University of A Coruña (UDC), A Coruña, Spain., Vallejo JA; Microbiology Research Group, Institute of Biomedical Research (INIBIC) - Interdisciplinary Center for Chemistry and Biology (CICA), University of A Coruña (UDC) - CIBER de Enfermedades Infecciosas (CIBERINFEC-ISCIII), Edificio Sur, Hospital Universitario A Coruña, As Xubias, A Coruña, Spain., Rumbo-Feal S; Microbiology Research Group, Institute of Biomedical Research (INIBIC) - Interdisciplinary Center for Chemistry and Biology (CICA), University of A Coruña (UDC) - CIBER de Enfermedades Infecciosas (CIBERINFEC-ISCIII), Edificio Sur, Hospital Universitario A Coruña, As Xubias, A Coruña, Spain., Conde-Pérez K; Microbiology Research Group, Institute of Biomedical Research (INIBIC) - Interdisciplinary Center for Chemistry and Biology (CICA), University of A Coruña (UDC) - CIBER de Enfermedades Infecciosas (CIBERINFEC-ISCIII), Edificio Sur, Hospital Universitario A Coruña, As Xubias, A Coruña, Spain., Aja-Macaya P; Microbiology Research Group, Institute of Biomedical Research (INIBIC) - Interdisciplinary Center for Chemistry and Biology (CICA), University of A Coruña (UDC) - CIBER de Enfermedades Infecciosas (CIBERINFEC-ISCIII), Edificio Sur, Hospital Universitario A Coruña, As Xubias, A Coruña, Spain., Ladra S; Database Laboratory, Research Center for Information and Communication Technologies (CITIC), University of A Coruña (UDC), A Coruña, Spain., Moreno-Flores A; Servicio de Microbiología, Hospital Universitario Lucus Augusti, Lugo, Spain., Gude-González MJ; Servicio de Microbiología, Hospital Universitario Lucus Augusti, Lugo, Spain., Coira A; Department of Microbiology, Complexo Hospitalario Universitario de Santiago de Compostela. SERGAS - Microbiology Research Group, Institute of Biomedical Research (IDIS), Santiago de Compostela, Spain., Aguilera A; Department of Microbiology, Complexo Hospitalario Universitario de Santiago de Compostela. SERGAS - Microbiology Research Group, Institute of Biomedical Research (IDIS), Santiago de Compostela, Spain., Costa-Alcalde JJ; Department of Microbiology, Complexo Hospitalario Universitario de Santiago de Compostela. SERGAS - Microbiology Research Group, Institute of Biomedical Research (IDIS), Santiago de Compostela, Spain., Trastoy R; Department of Microbiology, Complexo Hospitalario Universitario de Santiago de Compostela. SERGAS - Microbiology Research Group, Institute of Biomedical Research (IDIS), Santiago de Compostela, Spain., Barbeito-Castiñeiras G; Department of Microbiology, Complexo Hospitalario Universitario de Santiago de Compostela. SERGAS - Microbiology Research Group, Institute of Biomedical Research (IDIS), Santiago de Compostela, Spain., García-Souto D; CiMUS, Universidade de Santiago de Compostela, Santiago de Compostela, Spain., Tubio JMC; CiMUS, Universidade de Santiago de Compostela, Santiago de Compostela, Spain.; Department of Zoology, Genetics and Physic Anthropology, Santiago de Compostela, Spain., Trigo-Daporta M; Clinical Microbiology Unit, Complexo Hospitalario Universitario de Pontevedra, Pontevedra, Spain., Camacho-Zamora P; Clinical Microbiology Unit, Complexo Hospitalario Universitario de Pontevedra, Pontevedra, Spain., Costa JG; Servicio de Microbiología, Complejo Hospitalario Universitario de Ourense, Ourense, Spain., González-Domínguez M; Servicio de Microbiología, Complejo Hospitalario Universitario de Ourense, Ourense, Spain., Canoura-Fernández L; Servicio de Microbiología, Complejo Hospitalario Universitario de Ourense, Ourense, Spain., Glez-Peña D; CINBIO, Universidade de Vigo, Vigo, Spain.; Galicia Sur Health Research Institute (IIS Galicia Sur), SERGAS-UVIGO, Vigo, Spain., Pérez-Castro S; Department of Microbiology, Complexo Hospitalario Universitario de Vigo (CHUVI), SERGAS, Vigo, Spain.; Microbiology and Infectology Research Group, Galicia Sur Health Research Institute (IIS Galicia Sur), SERGAS-UVIGO, Vigo, Spain., Cabrera JJ; Department of Microbiology, Complexo Hospitalario Universitario de Vigo (CHUVI), SERGAS, Vigo, Spain.; Microbiology and Infectology Research Group, Galicia Sur Health Research Institute (IIS Galicia Sur), SERGAS-UVIGO, Vigo, Spain., Daviña-Núñez C; Microbiology and Infectology Research Group, Galicia Sur Health Research Institute (IIS Galicia Sur), SERGAS-UVIGO, Vigo, Spain., Godoy-Diz M; Department of Microbiology, Complexo Hospitalario Universitario de Vigo (CHUVI), SERGAS, Vigo, Spain., Treinta-Álvarez AB; Department of Microbiology, Complexo Hospitalario Universitario de Vigo (CHUVI), SERGAS, Vigo, Spain., Veiga MI; Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal.; ICVS/3B's-PT Government Associate Laboratory, Guimarães, Portugal., Sousa JC; Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal.; ICVS/3B's-PT Government Associate Laboratory, Guimarães, Portugal., Osório NS; Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal.; ICVS/3B's-PT Government Associate Laboratory, Guimarães, Portugal., Comas I; Tuberculosis Genomics Unit, BioMedicine Institute of Valencia, Spanish Research Council (CSIC), Valencia, Spain.; CIBER in Epidemiology and Public Health, Madrid, Spain.; Joint Research Unit 'Infection and Public Health', FISABIO-University of Valencia, Valencia, Spain., González-Candelas F; CIBER in Epidemiology and Public Health, Madrid, Spain.; Joint Research Unit 'Infection and Public Health', FISABIO-University of Valencia, Valencia, Spain.; Institute for Integrative Systems Biology (I2SysBio), University of Valencia-CSIC, Valencia, Spain., Hong SL; Department of Microbiology, Immunology and Transplantation, Rega Institute, Laboratory of Clinical and Epidemiological Virology, KU Leuven, University of Leuven, Leuven, Belgium., Bollen N; Department of Microbiology, Immunology and Transplantation, Rega Institute, Laboratory of Clinical and Epidemiological Virology, KU Leuven, University of Leuven, Leuven, Belgium., Dellicour S; Department of Microbiology, Immunology and Transplantation, Rega Institute, Laboratory of Clinical and Epidemiological Virology, KU Leuven, University of Leuven, Leuven, Belgium.; Spatial Epidemiology Lab, Université Libre de Bruxelles, Brussels, Belgium., Baele G; Department of Microbiology, Immunology and Transplantation, Rega Institute, Laboratory of Clinical and Epidemiological Virology, KU Leuven, University of Leuven, Leuven, Belgium., Suchard MA; Department of Biostatistics, Fielding School of Public Health, University of California Los Angeles, Los Angeles, California, USA.; Department of Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA.; Department of Computational Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA., Lemey P; Department of Microbiology, Immunology and Transplantation, Rega Institute, Laboratory of Clinical and Epidemiological Virology, KU Leuven, University of Leuven, Leuven, Belgium.; Global Virus Network (GVN), Baltimore, Maryland, USA., Agulla A; Servicio de Microbiología del Complejo Hospitalario Universitario de Ferrol, Ferrol, Spain., Bou G; Microbiology Research Group, Institute of Biomedical Research (INIBIC) - Interdisciplinary Center for Chemistry and Biology (CICA), University of A Coruña (UDC) - CIBER de Enfermedades Infecciosas (CIBERINFEC-ISCIII), Edificio Sur, Hospital Universitario A Coruña, As Xubias, A Coruña, Spain., Alonso-García P; Servicio de Microbiología, Hospital Universitario Lucus Augusti, Lugo, Spain., Pérez-Del-Molino ML; Department of Microbiology, Complexo Hospitalario Universitario de Santiago de Compostela. SERGAS - Microbiology Research Group, Institute of Biomedical Research (IDIS), Santiago de Compostela, Spain., García-Campello M; Clinical Microbiology Unit, Complexo Hospitalario Universitario de Pontevedra, Pontevedra, Spain., Paz-Vidal I; Servicio de Microbiología, Complejo Hospitalario Universitario de Ourense, Ourense, Spain., Regueiro B; Department of Microbiology, Complexo Hospitalario Universitario de Vigo (CHUVI), SERGAS, Vigo, Spain.; Microbiology and Infectology Research Group, Galicia Sur Health Research Institute (IIS Galicia Sur), SERGAS-UVIGO, Vigo, Spain., Posada D; CINBIO, Universidade de Vigo, Vigo, Spain.; Galicia Sur Health Research Institute (IIS Galicia Sur), SERGAS-UVIGO, Vigo, Spain.; Department of Biochemistry, Genetics, and Immunology, Universidade de Vigo, Vigo, Spain.
Jazyk:	angličtina
Zdroj:	Journal of medical virology [J Med Virol] 2024 Jul; Vol. 96 (7), pp. e29773.
DOI:	10.1002/jmv.29773
Abstrakt:	The dynamics of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission are influenced by a variety of factors, including social restrictions and the emergence of distinct variants. In this study, we delve into the origins and dissemination of the Alpha, Delta, and Omicron-BA.1 variants of concern in Galicia, northwest Spain. For this, we leveraged genomic data collected by the EPICOVIGAL Consortium and from the GISAID database, along with mobility information from other Spanish regions and foreign countries. Our analysis indicates that initial introductions during the Alpha phase were predominantly from other Spanish regions and France. However, as the pandemic progressed, introductions from Portugal and the United States became increasingly significant. The number of detected introductions varied from 96 and 101 for Alpha and Delta to 39 for Omicron-BA.1. Most of these introductions left a low number of descendants (<10), suggesting a limited impact on the evolution of the pandemic in Galicia. Notably, Galicia's major coastal cities emerged as critical hubs for viral transmission, highlighting their role in sustaining and spreading the virus. This research emphasizes the critical role of regional connectivity in the spread of SARS-CoV-2 and offers essential insights for enhancing public health strategies and surveillance measures. (© 2024 The Author(s). Journal of Medical Virology published by Wiley Periodicals LLC.)
Databáze:	MEDLINE
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