A Pediatric Case of Fusobacterium necrophorum Mastoiditis and Meningitis Case Report in a Healthy Child and Review of the Literature.

Autor: Feenstra E; Pediatrics, (Pediatric) Critical Care, Pediatric Neurology, Radiology, General Internal Medicine, Infectious Diseases and Tropical Medicine, Antwerp University Hospital, Edegem, Belgium., Van Roest A; Pediatrics and Microbiology, AZ Turnhout, Turnhout, Belgium., Boes J; Pediatrics and Microbiology, AZ Turnhout, Turnhout, Belgium., Spiritus T; Pediatrics and Microbiology, AZ Turnhout, Turnhout, Belgium., Kenis S; Pediatrics, (Pediatric) Critical Care, Pediatric Neurology, Radiology, General Internal Medicine, Infectious Diseases and Tropical Medicine, Antwerp University Hospital, Edegem, Belgium., Duval ELIM; Pediatrics, (Pediatric) Critical Care, Pediatric Neurology, Radiology, General Internal Medicine, Infectious Diseases and Tropical Medicine, Antwerp University Hospital, Edegem, Belgium.; Laboratory of Experimental Medicine and Pediatrics (LEMP), University of Antwerp, Antwerp, Belgium., Vanden Bossche S; Pediatrics, (Pediatric) Critical Care, Pediatric Neurology, Radiology, General Internal Medicine, Infectious Diseases and Tropical Medicine, Antwerp University Hospital, Edegem, Belgium., Vanden Driessche K; Pediatrics, (Pediatric) Critical Care, Pediatric Neurology, Radiology, General Internal Medicine, Infectious Diseases and Tropical Medicine, Antwerp University Hospital, Edegem, Belgium., Jorens PG; Pediatrics, (Pediatric) Critical Care, Pediatric Neurology, Radiology, General Internal Medicine, Infectious Diseases and Tropical Medicine, Antwerp University Hospital, Edegem, Belgium.; Laboratory of Experimental Medicine and Pediatrics (LEMP), University of Antwerp, Antwerp, Belgium.
Jazyk: angličtina
Zdroj: Case reports in pediatrics [Case Rep Pediatr] 2024 Jun 12; Vol. 2024, pp. 6365796. Date of Electronic Publication: 2024 Jun 12 (Print Publication: 2024).
DOI: 10.1155/2024/6365796
Abstrakt: In infants and children, bacterial meningitis caused by anaerobic bacteria is rare. However, a serious infection with the anaerobe Fusobacterium necrophorum can occur in previously healthy children with a peak incidence in preschool children and in adolescents. As the clinical presentation can be very similar to meningitis caused by aerobic bacteria, one should consider Fusobacterium necrophorum as the causative agent when preceded by or associated with otitis media with purulent otorrhea or mastoiditis, in combination with minimal or no improvement on empiric antibiotic treatment. As this pathogen can be difficult to culture, anaerobic cultures should be obtained. Prompt treatment with a third-generation cephalosporin and metronidazole should be initiated once suspected or confirmed. Surgical source control is often necessary, but even with adequate and prompt treatment, the morbidity and mortality in children with a Fusobacterium necrophorum meningitis remains high. In this report, we describe a case of Fusobacterium necrophorum meningitis in a previously healthy child and review the available literature.
Competing Interests: The authors declare that there are no conflicts of interest regarding the publication of this article. Moreover, the patient is sufficiently anonymized according to the ICMJE guidelines.
(Copyright © 2024 Elizabeth Feenstra et al.)
Databáze: MEDLINE
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