Optimization of window settings for coronary arteries assessment using spectral CT-derived virtual monoenergetic imaging.

Autor: D'Angelo T; Diagnostic and Interventional Radiology Unit, BIOMORF Department, University Hospital 'Policlinico G. Martino', Via Consolare Valeria 1, 98100, Messina, Italy. tommasodang@gmail.com.; Department of Radiology and Nuclear Medicine, Erasmus MC, Doctor Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands. tommasodang@gmail.com., Mastrodicasa D; Department of Radiology, Stanford University School of Medicine, 453 Quarry Rd, MC 5659, Palo Alto, CA 94304-5659, USA., Lanzafame LRM; Diagnostic and Interventional Radiology Unit, BIOMORF Department, University Hospital 'Policlinico G. Martino', Via Consolare Valeria 1, 98100, Messina, Italy., Yel I; Division of Experimental Imaging, Department of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt, Germany., Koch V; Division of Experimental Imaging, Department of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt, Germany., Gruenewald LD; Division of Experimental Imaging, Department of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt, Germany., Sharma SP; Department of Radiology and Nuclear Medicine, Erasmus MC, Doctor Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands., Ascenti V; Department of Radiology, Policlinico Universitario Ospedale Maggiore, Via Francesco Sforza 35, 20122, Milan, Italy., Micari A; Diagnostic and Interventional Radiology Unit, BIOMORF Department, University Hospital 'Policlinico G. Martino', Via Consolare Valeria 1, 98100, Messina, Italy., Blandino A; Diagnostic and Interventional Radiology Unit, BIOMORF Department, University Hospital 'Policlinico G. Martino', Via Consolare Valeria 1, 98100, Messina, Italy., Vogl TJ; Division of Experimental Imaging, Department of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt, Germany., Mazziotti S; Diagnostic and Interventional Radiology Unit, BIOMORF Department, University Hospital 'Policlinico G. Martino', Via Consolare Valeria 1, 98100, Messina, Italy., Budde RPJ; Department of Radiology and Nuclear Medicine, Erasmus MC, Doctor Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands., Booz C; Division of Experimental Imaging, Department of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt, Germany.
Jazyk: angličtina
Zdroj: La Radiologia medica [Radiol Med] 2024 Jul; Vol. 129 (7), pp. 999-1007. Date of Electronic Publication: 2024 Jun 27.
DOI: 10.1007/s11547-024-01835-6
Abstrakt: Purpose: To determine the optimal window setting for virtual monoenergetic images (VMI) reconstructed from dual-layer spectral coronary computed tomography angiography (DE-CCTA) datasets.
Material and Methods: 50 patients (30 males; mean age 61.1 ± 12.4 years who underwent DE-CCTA from May 2021 to June 2022 for suspected coronary artery disease, were retrospectively included. Image quality assessment was performed on conventional images and VMI reconstructions at 70 and 40 keV. Objective image quality was assessed using contrast-to-noise ratio (CNR). Two independent observers manually identified the best window settings (B-W/L) for VMI 70 and VMI 40 visualization. B-W/L were then normalized with aortic attenuation using linear regression analysis to obtain the optimized W/L (O-W/L) settings. Additionally, subjective image quality was evaluated using a 5-point Likert scale, and vessel diameters were measured to examine any potential impact of different W/L settings.
Results: VMI 40 demonstrated higher CNR values compared to conventional and VMI 70. B-W/L settings identified were 1180/280 HU for VMI 70 and 3290/900 HU for VMI 40. Subsequent linear regression analysis yielded O-W/L settings of 1155/270 HU for VMI 70 and 3230/880 HU for VMI 40. VMI 40 O-W/L received the highest scores for each parameter compared to conventional (all p < 0.0027). Using O-W/L settings for VMI 70 and VMI 40 did not result in significant differences in vessel measurements compared to conventional images.
Conclusion: Optimization of VMI requires adjustments in W/L settings. Our results recommend W/L settings of 1155/270 HU for VMI 70 and 3230/880 HU for VMI 40.
(© 2024. The Author(s).)
Databáze: MEDLINE
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