Hepatitis E virus in children and adolescents living in an urban environment in central Argentina: An explorative study.

Autor:	Cervella LL; Hospital Infantil Municipal, Municipalidad de Córdoba, Luis de Góngora 550, Alta Córdoba, CP, 5000, Córdoba, Argentina., García Oro C; Hospital Infantil Municipal, Municipalidad de Córdoba, Luis de Góngora 550, Alta Córdoba, CP, 5000, Córdoba, Argentina., Fantilli AC; Instituto de Virología 'Dr. J. M. Vanella', CONICET, Facultad de Ciencias Médicas, Universidad Nacional de Córdoba, Enfermera Gordillo Gómez s/n, Ciudad Universitaria, CP, 5016, Córdoba, Argentina., Di Cola G; Instituto de Virología 'Dr. J. M. Vanella', CONICET, Facultad de Ciencias Médicas, Universidad Nacional de Córdoba, Enfermera Gordillo Gómez s/n, Ciudad Universitaria, CP, 5016, Córdoba, Argentina., Martínez Wassaf MG; LACE Laboratorios, Av. Vélez Sársfield 528, Centro, CP, 5000, Córdoba, Argentina., Oropeza G; Hospital Infantil Municipal, Municipalidad de Córdoba, Luis de Góngora 550, Alta Córdoba, CP, 5000, Córdoba, Argentina., Castro GM; Laboratorio Central de la Provincia, Ministerio de Salud, Gobierno de la Provincia de Córdoba, Tránsito Cáceres de Allende 421, Nueva Córdoba, CP, 5000, Córdoba, Argentina., Sicilia P; Laboratorio Central de la Provincia, Ministerio de Salud, Gobierno de la Provincia de Córdoba, Tránsito Cáceres de Allende 421, Nueva Córdoba, CP, 5000, Córdoba, Argentina., Ré VE; Instituto de Virología 'Dr. J. M. Vanella', CONICET, Facultad de Ciencias Médicas, Universidad Nacional de Córdoba, Enfermera Gordillo Gómez s/n, Ciudad Universitaria, CP, 5016, Córdoba, Argentina., Pisano MB; Instituto de Virología 'Dr. J. M. Vanella', CONICET, Facultad de Ciencias Médicas, Universidad Nacional de Córdoba, Enfermera Gordillo Gómez s/n, Ciudad Universitaria, CP, 5016, Córdoba, Argentina.
Jazyk:	angličtina
Zdroj:	Heliyon [Heliyon] 2024 Jun 03; Vol. 10 (11), pp. e32284. Date of Electronic Publication: 2024 Jun 03 (Print Publication: 2024).
DOI:	10.1016/j.heliyon.2024.e32284
Abstrakt:	In Argentina, circulation of hepatitis E virus (HEV) genotype 3 has been described, producing sporadic cases of acute and chronic hepatitis. Limited information is available regarding HEV infection in children, so we aimed to investigate this virus in a pediatric population from the country. Serum samples from Argentine children (0-18 years old) (n = 213) were studied for IgG anti-HEV, IgM anti-HEV and RNA-HEV: 202 samples belonged to individuals attending health-care centers for routine check-ups, and 11 samples from patients with acute hepatitis of unknown etiology. Seropositivity for IgG anti-HEV was 1.49 % (3/202). One sample from an 18-years-old female patient with acute hepatitis tested positive for IgM anti-HEV detection, negative for IgG anti-HEV and RNA-HEV, but also positive for IgM anti-EBV. The HEV prevalence was low and showed circulation among children in central Argentina. Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. (© 2024 The Authors.)
Databáze:	MEDLINE
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