PARATHYROID ADENOMA PRESENTING AS MULTIPLE BROWN TUMORS AND SEVERE ASYMPTOMATIC HYPERCALCEMIA.

Autor: Wasnik DV; All India Institute of Medical Sciences - General Medicine, Nagpur, India., Khot RS; All India Institute of Medical Sciences - General Medicine, Nagpur, India., Joshi PP; All India Institute of Medical Sciences - General Medicine, Nagpur, India., Rathod BD; All India Institute of Medical Sciences - General Medicine, Nagpur, India., Narang U; All India Institute of Medical Sciences - General Medicine, Nagpur, India., Ratnaparkhi C; All India Institute of Medical Sciences - Radiodiagnosis, Nagpur, India.
Jazyk: angličtina
Zdroj: Acta endocrinologica (Bucharest, Romania : 2005) [Acta Endocrinol (Buchar)] 2023 Oct-Dec; Vol. 19 (4), pp. 508-511. Date of Electronic Publication: 2024 Jun 24.
DOI: 10.4183/aeb.2023.508
Abstrakt: Introduction: Primary hyperparathyroidism may have several presentations, varying from an incidental asymptomatic biochemical finding to gastrointestinal, psychiatric, renal and bone manifestations. Brown tumors are rare non-neoplastic lesions because of abnormal bone metabolism. Herein, we describe a patient who presented with lytic bony lesions and severe asymptomatic hypercalcemia due to parathyroid adenoma.
Case Presentation: A 38-year-old male presented with multiple painful bony lesions over upper and lower limbs. Radiographs of long bones showed multiple lytic lesions with cortical thinning. Investigations revealed hypercalcemia and hyperparathyroidism. A radionuclide scan showed parathyroid adenoma. The patient was treated for hypercalcemia and a parathyroidectomy was performed.
Conclusions: In a patient presenting with multiple bony swellings and asymptomatic hypercalcemia, hyperparathyroidism should be suspected. Parathyroid adenoma is a treatable cause of primary hyperparathyroidism.
Competing Interests: The authors declare that they have no conflict of interest.
(©2023 Acta Endocrinologica (Buc).)
Databáze: MEDLINE