| Autor: |
Sun H; School of Mechanical Engineering, University of Shanghai for Science and Technology, Shanghai 200093, P. R. China., Ding X; School of Mechanical Engineering, University of Shanghai for Science and Technology, Shanghai 200093, P. R. China., Xu S; Shanghai Special Equipment Supervision and Inspection Technology Research Institute, Shanghai 200062, P. R. China., Duan P; School of Mechanical Engineering, University of Shanghai for Science and Technology, Shanghai 200093, P. R. China., Xiong M; School of Mechanical Engineering, University of Shanghai for Science and Technology, Shanghai 200093, P. R. China., Zhang H; School of Mechanical Engineering, University of Shanghai for Science and Technology, Shanghai 200093, P. R. China. |
| Jazyk: |
čínština |
| Zdroj: |
Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi [Sheng Wu Yi Xue Gong Cheng Xue Za Zhi] 2024 Jun 25; Vol. 41 (3), pp. 595-603. |
| DOI: |
10.7507/1001-5515.202311037 |
| Abstrakt: |
The stiffness of an ideal fracture internal fixation implant should have a time-varying performance, so that the fracture can generate reasonable mechanical stimulation at different healing stages, and biodegradable materials meet this performance. A topology optimization design method for composite structures of fracture internal fixation implants with time-varying stiffness is proposed, considering the time-dependent degradation process of materials. Using relative density and degradation residual rate to describe the distribution and degradation state of two materials with different degradation rates and elastic modulus, a coupled mathematical model of degradation simulation mechanical analysis was established. Biomaterial composite structures were designed based on variable density method to exhibit time-varying stiffness characteristics. Taking the bone plate used for the treatment of tibial fractures as an example, a composite structure bone plate with time-varying stiffness characteristics was designed using the proposed method. The optimization results showed that material 1 with high stiffness formed a columnar support structure, while material 2 with low stiffness was distributed at the degradation boundary and inside. Using a bone remodeling simulation model, the optimized bone plates were evaluated. After 11 months of remodeling, the average elastic modulus of callus using degradable time-varying stiffness plates, titanium alloy plates, and stainless steel plates were 8 634 MPa, 8 521 MPa, and 8 412 MPa, respectively, indicating that the use of degradable time-varying stiffness plates would result in better remodeling effects on the callus. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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