Integrative Approach to Risk Factors in Simple Chronic Obstructive Airway Diseases of the Lung or Associated with Metabolic Syndrome-Analysis and Prediction.

Autor: Streba L; Department of Oncology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania., Popovici V; Center for Mountain Economics, 'Costin C. Kiriţescu' National Institute of Economic Research (INCE-CEMONT), Romanian Academy, 725700 Vatra-Dornei, Romania., Mihai A; Department of Pulmonology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania., Mititelu M; Faculty of Pharmacy, 'Carol Davila' University of Medicine and Pharmacy, 020956 Bucharest, Romania., Lupu CE; Department of Mathematics and Informatics, Faculty of Pharmacy, 'Ovidius' University of Constanta, 900001 Constanta, Romania., Matei M; Department of Histology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania., Vladu IM; Department of Diabetes, Nutrition and Metabolic Diseases, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania., Iovănescu ML; Department of Cardiology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania., Cioboată R; Department of Pulmonology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania., Călărașu C; Department of Pulmonology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania., Busnatu ȘS; Department of Cardio-Thoracic Pathology, Faculty of Medicine, 'Carol Davila' University of Medicine and Pharmacy, 050474 Bucharest, Romania., Streba CT; Department of Pulmonology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Jazyk: angličtina
Zdroj: Nutrients [Nutrients] 2024 Jun 13; Vol. 16 (12). Date of Electronic Publication: 2024 Jun 13.
DOI: 10.3390/nu16121851
Abstrakt: We conducted an epidemiological non-interventional cross-sectional and case-control study from 1 January 2023 until 26 May 2023 in Oltenia region, southwestern Romania. Throughout the research, 160 consecutive patients were included from two different clinical departments (1-Pneumology; 2-Diabetes and Nutritional Diseases). Subjects were voluntary adult individuals of any gender who expressed their written consent. The clinical data of the patients were correlated with the exposure to behavioral risk factors (diet, lifestyle, exposure to pollutants) to identify some negative implications that could be corrected to improve the quality of life of patients with simple chronic obstructive airway diseases of the lung or associated with metabolic syndrome (MS). In the first group of patients with respiratory diseases, there was a higher degree of exposure to toxic substances (43.75%) compared to the second group of patients with diabetes (18.75%); it is also noticeable that in the first group, there were noticeably fewer individuals who have never smoked (25%) compared to the second group (50%). Respiratory function impairment was observed to be more severe in overweight individuals. In the group of patients with known lung diseases, a positive correlation was noted between the presence of MS and respiratory dysfunctions of greater severity. Additionally, potential exacerbating factors affecting lung function, such as direct exposure to toxins and smoking, were considered. Potential secondary factors exacerbating respiratory dysfunction were considered by correlating biochemical parameters with dietary habits. These included reduced consumption of vegetables, inadequate hydration, and increased intake of sweets and products high in saturated or trans fats (commonly found in junk food), primarily due to their potential contribution to excess weight. Compared to patients without MS, the severity of the pulmonary function impairment correlated with the number of criteria met for MS and, independently, with an increase in weight.
Databáze: MEDLINE