Autor: |
Costa B; i3N and Department of Physics, University of Aveiro, Campus Universitário de Santiago, 3810-193 Aveiro, Portugal., Carvalho J; i3N and Department of Physics, University of Aveiro, Campus Universitário de Santiago, 3810-193 Aveiro, Portugal., Gavinho S; i3N and Department of Physics, University of Aveiro, Campus Universitário de Santiago, 3810-193 Aveiro, Portugal., Vieira T; i3N/CENIMAT, Physics Department, NOVA School of Science and Technology, Campus de Caparica, NOVA University Lisbon, 2829-516 Caparica, Portugal., Silva JC; i3N/CENIMAT, Physics Department, NOVA School of Science and Technology, Campus de Caparica, NOVA University Lisbon, 2829-516 Caparica, Portugal., Soares PIP; i3N/CENIMAT, Science Materials Department, Faculty of Sciences and Technology, Nova University of Lisbon, 2829-516 Caparica, Portugal., Valente MA; i3N and Department of Physics, University of Aveiro, Campus Universitário de Santiago, 3810-193 Aveiro, Portugal., Soreto S; i3N and Department of Physics, University of Aveiro, Campus Universitário de Santiago, 3810-193 Aveiro, Portugal., Graça M; i3N and Department of Physics, University of Aveiro, Campus Universitário de Santiago, 3810-193 Aveiro, Portugal. |
Abstrakt: |
Cancer is a major worldwide public health problem. Although there have already been astonishing advances in cancer diagnosis and treatment, the scientific community continues to make huge efforts to develop new methods to treat cancer. The main objective of this work is to prepare, using a green sol-gel method with coconut water powder (CWP), a new nanocomposite with a mixture of Gd 3 Fe 5 O 12 and ZnFe 2 O 4 , which has never been synthesized previously. Therefore, we carried out a structural (DTA-TG and X-ray diffraction), morphological (SEM), and magnetic (VSM and hyperthermia) characterization of the prepared samples. The prepared nanocomposite denoted a saturation magnetization of 11.56 emu/g at room temperature with a ferromagnetic behavior and with a specific absorption rate (SAR) value of 0.5 ± 0.2 (W/g). Regarding cytotoxicity, for concentrations < 10 mg/mL, it does not appear to be toxic. Although the obtained results were interesting, the high particle size was identified as a problem for the use of this nanocomposite. |