Atrial Fibrillation and Mortality after Gastrointestinal Surgery: Insights from a Systematic Review and Meta-Analysis.

Autor:	Palcău AC; 'Carol Davila' University of Medicine and Pharmacy, 050474 Bucharest, Romania.; General Surgery Department, University Emergency Hospital of Bucharest, 050098 Bucharest, Romania., Șerbănoiu LI; 'Carol Davila' University of Medicine and Pharmacy, 050474 Bucharest, Romania.; Department of Cardiology, Emergency Hospital 'Bagdasar-Arseni', 050474 Bucharest, Romania., Ion D; 'Carol Davila' University of Medicine and Pharmacy, 050474 Bucharest, Romania.; General Surgery Department, University Emergency Hospital of Bucharest, 050098 Bucharest, Romania., Păduraru DN; 'Carol Davila' University of Medicine and Pharmacy, 050474 Bucharest, Romania.; General Surgery Department, University Emergency Hospital of Bucharest, 050098 Bucharest, Romania., Bolocan A; 'Carol Davila' University of Medicine and Pharmacy, 050474 Bucharest, Romania.; General Surgery Department, University Emergency Hospital of Bucharest, 050098 Bucharest, Romania., Mușat F; 'Carol Davila' University of Medicine and Pharmacy, 050474 Bucharest, Romania.; General Surgery Department, University Emergency Hospital of Bucharest, 050098 Bucharest, Romania., Andronic O; 'Carol Davila' University of Medicine and Pharmacy, 050474 Bucharest, Romania.; General Surgery Department, University Emergency Hospital of Bucharest, 050098 Bucharest, Romania., Busnatu ȘS; 'Carol Davila' University of Medicine and Pharmacy, 050474 Bucharest, Romania.; Department of Cardiology, Emergency Hospital 'Bagdasar-Arseni', 050474 Bucharest, Romania., Iliesiu AM; 'Carol Davila' University of Medicine and Pharmacy, 050474 Bucharest, Romania.; Department of Cardiology, 'TH. Burghele' Hospital, 050659 Bucharest, Romania.
Jazyk:	angličtina
Zdroj:	Journal of personalized medicine [J Pers Med] 2024 May 27; Vol. 14 (6). Date of Electronic Publication: 2024 May 27.
DOI:	10.3390/jpm14060571
Abstrakt:	Background: Heart failure, stroke and death are major dangers associated with atrial fibrillation (AF), a common abnormal heart rhythm. Having a gastrointestinal (GI) procedure puts patients at risk for developing AF, especially after large abdominal surgery. Although earlier research has shown a possible connection between postoperative AF and higher mortality, the exact nature of this interaction is yet uncertain. Methods: To investigate the relationship between AF and death after GI procedures, this research carried out a thorough meta-analysis and systematic review of randomized controlled studies or clinical trials. Finding relevant randomized controlled trials (RCTs) required a comprehensive search across many databases. Studies involving GI surgery patients with postoperative AF and mortality outcomes were the main focus of the inclusion criteria. We followed PRISMA and Cochrane Collaboration protocols for data extraction and quality assessment, respectively. Results: After GI surgery, there was no statistically significant difference in mortality between the AF and non-AF groups, according to an analysis of the available trials ( p = 0.97). The mortality odds ratio (OR) was 1.03 (95% CI [0.24, 4.41]), suggesting that there was no significant correlation. Nevertheless, there was significant heterogeneity throughout the trials, which calls for careful interpretation. Conclusion: Despite the lack of a significant link between AF and death after GI surgery in our study, contradictory data from other research highlight the intricacy of this relationship. Discrepancies may arise from variations in patient demographics, research methodology and procedural problems. These results emphasize the necessity for additional extensive and varied studies to fully clarify the role of AF in postoperative mortality in relation to GI procedures. Comprehending the subtleties of this correlation might enhance future patient outcomes and contribute to evidence-based therapeutic decision making.
Databáze:	MEDLINE
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