Consequences of Maternal Vitamin D Deficiency on Newborn Health.

Autor: Dragomir RE; Doctoral School, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania., Toader DO; Department of Obstetrics and Gynecology, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania., Gheoca Mutu DE; Discipline of Anatomy, Department 2-Morphological Sciences, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania., Dogaru IA; Doctoral School, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.; Discipline of Anatomy, Department 2-Morphological Sciences, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania., Răducu L; Discipline of Plastic Surgery, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania., Tomescu LC; Department of Obstetrics and Gynecology, 'Ovidius' University of Constanța, 900527 Constanța, Romania., Moleriu LC; Discipline of Medical Informatics and Biostatistics, Department 3-Functional Sciences, 'Victor Babeș' University of Medicine and Pharmacy, 300041 Timisoara, Romania., Bordianu A; Discipline of Plastic Surgery, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania., Petre I; Discipline of Medical Informatics and Biostatistics, Department 3-Functional Sciences, 'Victor Babeș' University of Medicine and Pharmacy, 300041 Timisoara, Romania., Stănculescu R; Doctoral School, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Jazyk: angličtina
Zdroj: Life (Basel, Switzerland) [Life (Basel)] 2024 May 31; Vol. 14 (6). Date of Electronic Publication: 2024 May 31.
DOI: 10.3390/life14060714
Abstrakt: Background and Objectives: Maternal-fetal gestational pathology is one of the biggest challenges in the field of health at this moment. The current study is designed to determine the effects of vitamin D on pregnancy, starting with the idea that impairment of vitamin D status is thought to be correlated with impairment of the newborn's health.
Materials and Methods: In this retrospective study, we tried to establish the link between vitamin D deficiency and maternal characteristics and also how it impacted the clinical status of the newborn. We analyzed a group of 260 patients: 130 pregnant women and 130 newborns, in whom vitamin D status was detected using the serum levels of 25-hydroxyvitamin D (25-(OH)D).
Results: The results showed that vitamin D deficiency has a high incidence among pregnant women, as was presented in many important international studies. Our study also showed a positive, direct correlation between the mother's and newborn's vitamin D status.
Conclusions: Taking into consideration that vitamin D deficiency has been correlated with many complications, both in maternal and newborn health, a serum level determination of 25-(OH)D is necessary in the first trimester of pregnancy, and after that, adequate supplementation is necessary in order to prevent any negative effects.
Databáze: MEDLINE
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