Subpectineal obturator nerve block reduces opioid consumption after hip arthroscopy: a triple-blind, randomized, placebo-controlled trial.

Autor:	Jessen C; Department of Anesthesiology and Intensive Care, PeriSCOP, Horsens Regional Hospital, Horsens, Denmark jessen_chr@hotmail.com.; Department of Clinical Medicine, Aarhus University Faculty of Health, Aarhus, Denmark., Espelund US; Department of Anesthesiology and Intensive Care, PeriSCOP, Horsens Regional Hospital, Horsens, Denmark.; Department of Clinical Medicine, Aarhus University Faculty of Health, Aarhus, Denmark., Brix LD; Department of Anesthesiology and Intensive Care, PeriSCOP, Horsens Regional Hospital, Horsens, Denmark.; Department of Clinical Medicine, Aarhus University Faculty of Health, Aarhus, Denmark., Nielsen TD; Department of Clinical Medicine, Aarhus University Faculty of Health, Aarhus, Denmark., Lund B; Department of Clinical Medicine, Aarhus University Faculty of Health, Aarhus, Denmark.; Department of Orthopedic Surgery, H-Hip, Horsens Regional Hospital, Horsens, Denmark., Bendtsen TF; Department of Clinical Medicine, Aarhus University Faculty of Health, Aarhus, Denmark.; Department of Anesthesiology, Aarhus University Hospital, Aarhus, Denmark.
Jazyk:	angličtina
Zdroj:	Regional anesthesia and pain medicine [Reg Anesth Pain Med] 2024 Jun 25. Date of Electronic Publication: 2024 Jun 25.
DOI:	10.1136/rapm-2024-105638
Abstrakt:	Background: Hip arthroscopy causes severe pain during the first few hours in the postoperative care unit. This is probably due to the intraoperative stretching of the hip joint capsule. Pain relief requires high doses of opioids which may prolong recovery and may cause opioid-related adverse events.The majority of hip joint capsule nociceptors are located anteriorly. The obturator nerve innervates the anteromedial part of the hip joint capsule. We hypothesized that a subpectineal obturator nerve block using 15 ml bupivacaine 5 mg/mL with added epinephrine 5 μg/mL would reduce the opioid consumption after hip arthroscopy. Methods: 40 ambulatory hip arthroscopy patients were enrolled in this randomized, triple-blind controlled trial. All patients were allocated to a preoperative active or placebo subpectineal obturator nerve block. The primary outcome was opioid consumption for the first 3 hours in the postanesthesia care unit. Secondary outcomes were pain, nausea, and hip adductor strength. Results: 34 patients were analyzed for the primary outcome. The mean intravenous morphine equivalent consumption in the subpectineal obturator nerve block group was 11.9 mg vs 19.7 mg in the placebo group (p<0.001). The hip adductor strength was significantly reduced in the active group. No other intergroup differences were observed regarding the secondary outcomes. Conclusion: We found a significant reduction in the opioid consumption for patients receiving an active subpectineal obturator nerve block. The postoperative intravenous morphine equivalent reduction the first painful 3 hours was reduced by 40% for patients receiving a subpectineal obturator nerve block in this randomized, triple-blind trial. Trial Registration Number: EudraCT database 2021-006575-42. Competing Interests: Competing interests: None declared. (© American Society of Regional Anesthesia & Pain Medicine 2024. No commercial re-use. See rights and permissions. Published by BMJ.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu