Leptomeningeal Carcinomatosis in Early Gastric Cancer: A Case Report and Literature Review.

Autor: Lucarini A; Surgical and Medical Department of Translational Medicine, Sant'Andrea Hospital, Sapienza University of Rome, Via di Grottarossa 1035, 00189 Rome, Italy., Arrivi G; Oncology Unit, Department of Clinical and Molecular Medicine, Sant' Andrea University Hospital, Sapienza University of Rome, 00189 Rome, Italy., Liotta E; Oncology Unit, Department of Clinical and Molecular Medicine, Sant' Andrea University Hospital, Sapienza University of Rome, 00189 Rome, Italy., Li Causi FS; Surgical and Medical Department of Translational Medicine, Sant'Andrea Hospital, Sapienza University of Rome, Via di Grottarossa 1035, 00189 Rome, Italy., Di Cicco L; Surgical and Medical Department of Translational Medicine, Sant'Andrea Hospital, Sapienza University of Rome, Via di Grottarossa 1035, 00189 Rome, Italy., Mazzuca F; Oncology Unit, Department of Clinical and Molecular Medicine, Sant' Andrea University Hospital, Sapienza University of Rome, 00189 Rome, Italy., Osti MF; Department of Medicine and Surgery and Translational Medicine, Radiotherapy Oncology, Sapienza University of Rome, Sant'Andrea Hospital, 00189 Rome, Italy., Balducci G; Surgical and Medical Department of Translational Medicine, Sant'Andrea Hospital, Sapienza University of Rome, Via di Grottarossa 1035, 00189 Rome, Italy., Mercantini P; Surgical and Medical Department of Translational Medicine, Sant'Andrea Hospital, Sapienza University of Rome, Via di Grottarossa 1035, 00189 Rome, Italy.
Jazyk: angličtina
Zdroj: Healthcare (Basel, Switzerland) [Healthcare (Basel)] 2024 Jun 12; Vol. 12 (12). Date of Electronic Publication: 2024 Jun 12.
DOI: 10.3390/healthcare12121184
Abstrakt: Leptomeningeal carcinomatosis (LC) is a rare site of metastasis in solid tumors, and it is associated with poor prognosis due to disabling symptoms and a scarcity of treatment options. This condition is an uncommon entity in gastric cancer (GC). We present a case of primary LC manifestation in a patient with an incidental diagnosis of localized node-negative GC. We additionally perform a literature review and discuss the diagnostic and therapeutic challenges. In conclusion, LC from GC represents a rare condition with a dramatic prognosis. Its diagnosis might be very challenging. A multidisciplinary approach appears to be the best strategy for the management of LC from GC.
Databáze: MEDLINE
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