| Autor: |
Keirsebelik MSG; Laboratório de Transmissores de Hematozoários, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro 21040-900, Brazil.; Laboratory of Microbiology, Parasitology and Hygiene, University of Antwerp, 1, 2610 Wilrijk-Antwerp, Belgium., David MR; Laboratório de Transmissores de Hematozoários, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro 21040-900, Brazil., Pavan MG; Laboratório de Transmissores de Hematozoários, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro 21040-900, Brazil., Couto-Lima D; Laboratório de Transmissores de Hematozoários, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro 21040-900, Brazil., Palomino M; Laboratorio de Referência Nacional de Entomologia, Centro Nacional de Salud Pública, Instituto Nacional de Salud, Lima 15072, Peru., Rahman RU; Department of Biosciences, COMSATS University, Islamabad 45550, Pakistan., Hoffmann AA; Pest and Environmental Adaptation Research Group, Bio21 Institute, School of BioSciences, The University of Melbourne, 3052 Melbourne, Australia., Bahia AC; Laboratório de Bioquímica de Insetos e Parasitos, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21040-900, Brazil., Caljon G; Laboratory of Microbiology, Parasitology and Hygiene, University of Antwerp, 1, 2610 Wilrijk-Antwerp, Belgium., Maciel-de-Freitas R; Laboratório de Transmissores de Hematozoários, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro 21040-900, Brazil.; Bernhard Nocht Institute for Tropical Medicine, 20359 Hamburg, Germany. |
| Abstrakt: |
The mosquito Aedes aegypti is distributed worldwide and is recognized as the primary vector for dengue in numerous countries. To investigate whether the fitness cost of a single DENV-1 isolate varies among populations, we selected four Ae. aegypti populations from distinct localities: Australia (AUS), Brazil (BRA), Pakistan (PAK), and Peru (PER). Utilizing simple methodologies, we concurrently assessed survival rates and fecundity. Overall, DENV-1 infection led to a significant decrease in mosquito survival rates, with the exception of the PER population. Furthermore, infected Ae. aegypti from PAK, the population with the lowest infection rate among those tested, exhibited a noteworthy reduction in egg laying. These findings collectively suggest that local mosquito-virus adaptations may influence dengue transmission in endemic settings. |
