Phylogenetic group distribution and antibiotic resistance of Escherichia coli isolates in aquatic environments of a highly populated area.
| Autor: | Mansour R; Department of Biological Sciences, Faculty of Sciences, Beirut Arab University, P.O. Box 11-5020, Riad El Solh 11072809, Beirut, Lebanon., El-Dakdouki MH; Department of Chemistry, Faculty of Sciences, Beirut Arab University, P.O. Box 11-5020, Riad El Solh 11072809, Beirut, Lebanon., Mina S; Department of Medical Laboratory Sciences, Faculty of Health Sciences, Beirut Arab University, P.O. Box 11-5020, Riad El Solh 11072809, Beirut, Lebanon. |
|---|---|
| Jazyk: | angličtina |
| Zdroj: | AIMS microbiology [AIMS Microbiol] 2024 May 09; Vol. 10 (2), pp. 340-362. Date of Electronic Publication: 2024 May 09 (Print Publication: 2024). |
| DOI: | 10.3934/microbiol.2024018 |
| Abstrakt: | Background: Extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae including Escherichia coli ( E. coli ), are recognized as a global public health threat due to their multidrug-resistant (MDR) phenotypes and their rapid dissemination in aquatic environments. Nevertheless, studies investigating the prevalence and antimicrobial resistance (AMR) profile of ESBL-producing E. coli in Lebanese surface water are limited. Objective: This study aimed to assess the physicochemical properties and microbial contamination load and to determine the distribution of AMR patterns of ESBL-producing E. coli in surface water samples from different sites in the North Governorate of Lebanon. Methods: Water samples were collected from 25 major sites in North Lebanon. These samples were analyzed for the presence of total coliforms, E. coli , and fecal enterococci. Phenotypic and genetic characterizations were then performed for E. coli isolates to determine their resistance patterns and phylogenetic groups. Results: Fifty-six samples out of 100 samples were positive for ESBL-producing E. coli , mostly harboring bla Conclusion: Our results highlight the need to implement effective water monitoring strategies to control transmission of ESBL-producing E. coli in surface water and thus reduce the burden on human and animal health. Competing Interests: Conflict of interest: The authors declare no conflict of interest in this work. (© 2024 the Author(s), licensee AIMS Press.) |
| Databáze: | MEDLINE |
| Externí odkaz: |
|