The Evolving Surgical Paradigm of Scleral Allograft Bio-Tissue Use in Ophthalmic Surgery: Techniques and Clinical Indications for Ab-Externo and Ab-Interno Scleral Reinforcement.

Autor: De Francesco T; John A. Moran Eye Center, University of Utah, Salt Lake City, UT, USA.; Clinica de Olhos De Francesco, Fortaleza, Brazil., Ianchulev T; Department of Ophthalmology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Rhee DJ; Department of Ophthalmology and Visual Sciences, Case Western Reserve University School of Medicine, Cleveland, OH, USA., Gentile RC; Department of Ophthalmology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; NYU Long Island School of Medicine, Department of Ophthalmology, Mineola, NY, USA., Pasquale LR; Department of Ophthalmology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Ahmed IIK; John A. Moran Eye Center, University of Utah, Salt Lake City, UT, USA.; Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Canada.; Prism Eye Institute, Mississauga, Canada.
Jazyk: angličtina
Zdroj: Clinical ophthalmology (Auckland, N.Z.) [Clin Ophthalmol] 2024 Jun 21; Vol. 18, pp. 1789-1795. Date of Electronic Publication: 2024 Jun 21 (Print Publication: 2024).
DOI: 10.2147/OPTH.S462719
Abstrakt: To review the latest surgical advances and evolving clinical use of scleral bio-tissue for reinforcement in the eye and review the published literature on novel surgical applications of scleral allograft bio-tissue. Conventional surgical procedures for scleral reinforcement using homologous scleral allograft have been traditionally ab-externo interventions comprising of anterior or posterior reinforcement of the sclera for clinical indications such as trauma, scleromalacia, glaucoma drainage device coverage, scleral perforation, buckle repair as well as posterior reinforcement for pathologic myopia and staphyloma. There have been a few novel ab-interno uses of scleral bio-tissue for reinforcement in both retina and glaucoma. Over the last decade, there has been an increase in peer-reviewed publications on scleral reinforcement, reflecting more interest in its clinical applications. With favorable biological and biomechanical properties, scleral allograft may be an ideal substrate for an array of new applications and surgical uses.
Competing Interests: Dr Ticiana De Francesco is a consultant to Iantrek, outside the submitted work. Dr Tsontcho Ianchulev reports patents for and is the founder of Iantrek Inc. Dr Douglas Rhee is a consultant to Iantrek, during the conduct of the study; grants from and a consultant to AbbVie / Allergan, Alcon, Ocular Therapeutix, and Avellino, outside the submitted work. Dr Louis Pasquale is a paid consultant to Twenty Twenty. Dr Ike Ahmed is a consultant to Iantrek. The authors report no other conflicts of interest in this work.
(© 2024 De Francesco et al.)
Databáze: MEDLINE
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