Transcriptomic responses in the nervous system and correlated behavioural changes of a cephalopod exposed to ocean acidification.

Autor: Thomas JT; Australian Research Council Centre of Excellence for Coral Reef Studies, James Cook University, Townsville, QLD, 4811, Australia. jodi.thomas@my.jcu.edu.au.; Marine Climate Change Unit, Okinawa Institute of Science and Technology Graduate University, Okinawa, Japan. jodi.thomas@my.jcu.edu.au., Huerlimann R; Marine Climate Change Unit, Okinawa Institute of Science and Technology Graduate University, Okinawa, Japan., Schunter C; Swire Institute of Marine Science, School of Biological Sciences, The University of Hong Kong, Pok Fu Lam Road, Hong Kong SAR, China., Watson SA; Australian Research Council Centre of Excellence for Coral Reef Studies, James Cook University, Townsville, QLD, 4811, Australia.; College of Science and Engineering, James Cook University, Townsville, QLD, 4811, Australia.; Biodiversity and Geosciences Program, Queensland Museum Tropics, Queensland Museum, Townsville, QLD, 4810, Australia., Munday PL; Australian Research Council Centre of Excellence for Coral Reef Studies, James Cook University, Townsville, QLD, 4811, Australia.; College of Science and Engineering, James Cook University, Townsville, QLD, 4811, Australia., Ravasi T; Australian Research Council Centre of Excellence for Coral Reef Studies, James Cook University, Townsville, QLD, 4811, Australia.; Marine Climate Change Unit, Okinawa Institute of Science and Technology Graduate University, Okinawa, Japan.
Jazyk: angličtina
Zdroj: BMC genomics [BMC Genomics] 2024 Jun 25; Vol. 25 (1), pp. 635. Date of Electronic Publication: 2024 Jun 25.
DOI: 10.1186/s12864-024-10542-5
Abstrakt: Background: The nervous system is central to coordinating behavioural responses to environmental change, likely including ocean acidification (OA). However, a clear understanding of neurobiological responses to OA is lacking, especially for marine invertebrates.
Results: We evaluated the transcriptomic response of the central nervous system (CNS) and eyes of the two-toned pygmy squid (Idiosepius pygmaeus) to OA conditions, using a de novo transcriptome assembly created with long read PacBio ISO-sequencing data. We then correlated patterns of gene expression with CO 2 treatment levels and OA-affected behaviours in the same individuals. OA induced transcriptomic responses within the nervous system related to various different types of neurotransmission, neuroplasticity, immune function and oxidative stress. These molecular changes may contribute to OA-induced behavioural changes, as suggested by correlations among gene expression profiles, CO 2 treatment and OA-affected behaviours.
Conclusions: This study provides the first molecular insights into the neurobiological effects of OA on a cephalopod and correlates molecular changes with whole animal behavioural responses, helping to bridge the gaps in our knowledge between environmental change and animal responses.
(© 2024. The Author(s).)
Databáze: MEDLINE
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