Subacute Degeneration of Fibers After Vertical Parasagittal Hemispherotomy.

Autor: Hittinger M; Specialist Centre for Radiology, Schoen Clinic Vogtareuth, Vogtareuth, Germany. Markus.Hittinger@uk-augsburg.de.; Clinic for Diagnostic and Interventional Radiology and Neuroradiology, University Medical Centre, Augsburg, Germany. Markus.Hittinger@uk-augsburg.de., Hartlieb T; Specialist Centre for Paediatric Neurology, Neurorehabilitation and Epileptology, Schoen Clinic Vogtareuth, Vogtareuth, Germany., Heiland DH; Clinic for Neurosurgery, University Medical Centre, Freiburg, Germany.; Department of Neurosurgery, Medical Centre-University of Freiburg, Freiburg im Breisgau, Germany.; Department of Neurosurgery, University Hospital Erlangen, Erlangen, Germany., Heiland P; Department of Neurosurgery, University Hospital Erlangen, Erlangen, Germany., Pieper T; Specialist Centre for Paediatric Neurology, Neurorehabilitation and Epileptology, Schoen Clinic Vogtareuth, Vogtareuth, Germany., Staudt M; Specialist Centre for Paediatric Neurology, Neurorehabilitation and Epileptology, Schoen Clinic Vogtareuth, Vogtareuth, Germany.; Centre for Paediatric Palliative Care, Ludwig Maximilian University of Munich, Munich, Germany., Berlis A; Specialist Centre for Radiology, Schoen Clinic Vogtareuth, Vogtareuth, Germany.; Clinic for Diagnostic and Interventional Radiology and Neuroradiology, University Medical Centre, Augsburg, Germany., Kudernatsch M; Specialist Centre for Neurosurgery and Epilepsy Surgery, Schoen Clinic Vogtareuth, Vogtareuth, Germany., Mader I; Specialist Centre for Radiology, Schoen Clinic Vogtareuth, Vogtareuth, Germany.; University Children's Hospital, Basel, Switzerland.; Department of Neurosurgery, Medical Centre-University of Freiburg, Freiburg im Breisgau, Germany.
Jazyk: angličtina
Zdroj: Clinical neuroradiology [Clin Neuroradiol] 2024 Dec; Vol. 34 (4), pp. 851-858. Date of Electronic Publication: 2024 Jun 25.
DOI: 10.1007/s00062-024-01427-x
Abstrakt: Purpose: After vertical parasagittal hemispherotomy a restricted diffusion is often seen ipsilaterally and even distant from the adjacent resection margin. This retrospective cohort study analyses the anatomic site and the time course of the diffusion restriction after vertical parasagittal hemispherotomy.
Methods: Fifty-nine patients were included into this study, all of them having had one pre-operative and at least one post-operative MRI, including diffusion imaging at b‑values of 0 and 1000 s/mm 2 with a calculated ADC.
Results: Diffusion restriction occurred exclusively on the operated site in all patients. In the basal ganglia, diffusion restriction was present in 37 of 38 patients at the first postoperative day with a duration of 38 days. In the midbrain, the posterior limb of the internal capsule and the thalamus, a restricted diffusion became postoperatively prominent at day 9 in all three localizations, with a duration of 36, 34 and 36 days, respectively. The incidence of thalamic lesions was lower if a preoperative damage had occurred.
Conclusion: The restricted diffusion in the basal ganglia resembles direct effects of the operation at its edges, whereas the later appearing diffusion restriction in the midbrain and the posterior limb of the internal capsule rather belong to a degeneration of the descending fibers being transected by the hemispherotomy in the sense of a Wallerian degeneration. The presence of preoperative hemispheric lesions influences the development of diffusion restriction at subacute fiber degeneration.
Competing Interests: Conflict of interest M. Hittinger, T. Hartlieb, D.H. Heiland, P. Heiland, T. Pieper, M. Staudt, A. Berlis, M. Kudernatsch and I. Mader declare that they have no competing interests.
(© 2024. The Author(s).)
Databáze: MEDLINE
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