Atypical Toxocara canis -Induced Hepatic Visceral Larva Migrans: Diagnostic Challenges and Literature Review.

Autor: Huynh TM; Department of Internal Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Vietnam., Tran KQL; Department of Internal Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Vietnam., Dinh TH; Department of Internal Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Vietnam., Vo MM; Department of Gastroenterology, Cho Ray Hospital, Ho Chi Minh City, Vietnam., Pham TQ; Department of Pathology Cho Ray Hospital, Ho Chi Minh City, Vietnam., Vo TD; Department of Internal Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Vietnam.; Department of Gastroenterology, University Medical Center Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Jazyk: angličtina
Zdroj: The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi [Korean J Gastroenterol] 2024 Jun 25; Vol. 83 (6), pp. 247-252.
DOI: 10.4166/kjg.2024.051
Abstrakt: Toxocariasis, a zoonotic infection transmitted by Toxocara canis (from dogs) and Toxocara cati (from cats) larvae, poses rare but severe risks to humans. We present a case of hepatic visceral larva migrans (VLM) caused by Toxocara canis in a 21-year-old male with a history of close contact with a pet dog. Initial symptoms and imaging findings mimicked a pyogenic liver abscess. The initial laboratory investigations revealed neutrophilia and elevated levels of IgE. Despite broad-spectrum antibiotics, persistent fever prompted further investigation. Subsequent serological testing for Toxocara antibodies and histopathological analysis of liver tissue demonstrating eosinophil infiltrates and Charcot-Leyden crystals led to a confirmed diagnosis of a liver abscess caused by Toxocara canis . Serological testing for Toxocara antibodies and histopathological analysis of liver tissue confirmed a Toxocara canis -induced liver abscess. Albendazole treatment yielded significant clinical improvement. This case highlights the necessity of considering toxocariasis in liver abscess differentials, particularly in high-seroprevalence regions like Vietnam. Relying solely on serological tests may be insufficient, emphasizing the need for corroborative evidence, including invasive procedures like liver biopsy, for accurate hepatic toxocariasis diagnosis.
Databáze: MEDLINE