CENTRAL NERVOUS SYSTEM INFECTION BY GROUP A STREPTOCOCCUS IN CHILDREN IN SPAIN (2019-2023).

Autor:	Cobo-Vázquez E; From the Department of Pediatrics, Hospital Universitario Fundación de Alcorcón, Alcorcón.; PhD Program in Medicine, Universidad Complutense de Madrid., Aguilera-Alonso D; PhD Program in Medicine, Universidad Complutense de Madrid.; Pediatric Infectious Diseases Unit, Department of Pediatrics, Hospital General Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM).; Centro de Investigación Biomedica en Red de Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III, Madrid, Spain., Rello-Saltor V; Pediatric Infectious Diseases and Immunodeficiencies Unit, Hospital Universitari Vall d'Hebron., Gamell A; Pediatrics and Infectious Diseases Department, Hospital Clínico Universitario Virgen de la Arrixaca, Murcia, Spain., Mellado-Sola I; Department of Infectious Diseases and Tropical Pediatrics, Hospital Universitario La Paz and IdiPaz Foundation, Universidad Autónoma de Madrid, Red de Investigación Traslacional en Infectología Pediátrica (RITIP), Madrid, Spain., Oltra-Benavent M; Department of Pediatrics, Hospital Universitario y Politécnico La Fe, Valencia, Spain., Martín-Pedraz L; Department of Pediatrics, Complejo Hospitalario Regional de Málaga, Málaga, Spain., Manzanares-Casteleiro Á; Pediatric Infectious Diseases Unit, Department of Pediatrics, Hospital Universitario 12 de Octubre, Madrid, Spain., Carrasco-Colom J; Pediatric Infectious Diseases Unit, Department of Pediatrics, Hospital Universitari Son Espases, Palma de Mallorca, Spain., Cervantes E; Pediatrics and Infectious Diseases Department, Hospital Clínico Universitario Virgen de la Arrixaca, Murcia, Spain., Sanz-Santaeufemia F; Department of Pediatrics, Hospital Universitario Niño Jesús, Madrid, Spain., Colino-Gil E; Department of Pediatrics, Complejo Hospitalario Materno-Insular, Las Palmas de Gran Canaria, Spain., Jiménez-Montero B; Department of Pediatrics, Hospital Universitario Marqués de Valdecilla, Santander, Spain., Soto B; Department of Pediatrics, Hospital Universitario de Getafe, Getafe; and., Calvo C; Centro de Investigación Biomedica en Red de Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III, Madrid, Spain.; Department of Infectious Diseases and Tropical Pediatrics, Hospital Universitario La Paz and IdiPaz Foundation, Universidad Autónoma de Madrid, Red de Investigación Traslacional en Infectología Pediátrica (RITIP), Madrid, Spain., Saavedra-Lozano J; Pediatric Infectious Diseases Unit, Department of Pediatrics, Hospital General Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM).; Centro de Investigación Biomedica en Red de Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III, Madrid, Spain.; Universidad Complutense de Madrid, Madrid, Spain.
Jazyk:	angličtina
Zdroj:	The Pediatric infectious disease journal [Pediatr Infect Dis J] 2024 Jun 25. Date of Electronic Publication: 2024 Jun 25.
DOI:	10.1097/INF.0000000000004443
Abstrakt:	Central nervous system infections in children caused by group A Streptococcus are rare. This study, conducted across 52 hospitals in Spain from 2019 to 2023, identified 32 cases of central nervous system infections in children caused by group A Streptococcus, with a significant increase from October 2022 onward (1.1% vs. 5.9%, P = 0.002). Half required pediatric intensive care unit admission, 12.5% exhibited sequelae and the mortality rate was 6.2%. Mastoiditis was the predominant primary infection. Competing Interests: The authors have no funding or conflicts of interest to disclose. (Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.)
Databáze:	MEDLINE
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