Health Benefits of Palm Tocotrienol-Rich Fraction: A Systematic Review of Randomized Controlled Trials.

Autor: Looi AD; Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Jalan Lagoon Selatan, 47500 Sunway, Malaysia., Palanisamy UD; Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Jalan Lagoon Selatan, 47500 Sunway, Malaysia., Moorthy M; Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Jalan Lagoon Selatan, 47500 Sunway, Malaysia., Radhakrishnan AK; Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Jalan Lagoon Selatan, 47500 Sunway, Malaysia.
Jazyk: angličtina
Zdroj: Nutrition reviews [Nutr Rev] 2024 Jun 25. Date of Electronic Publication: 2024 Jun 25.
DOI: 10.1093/nutrit/nuae061
Abstrakt: Context: Vitamin E, a well-known antioxidant with numerous positive effects on human health, encompasses tocotrienol-rich fraction (TRF), a natural variant abundant in palm oil.
Objective: This systematic review analyzed findings from randomized controlled trials published until 2022 to evaluate the health impacts of palm TRF.
Data Sources: A literature search was performed in Cochrane Central Register of Controlled Trials (CENTRAL), PubMed, OVID Medline, SCOPUS, and Web of Science from inception until December 2022. Thirty studies involving 2646 patients, including both healthy individuals and those with underlying conditions, were identified.
Results: This review shows palm TRF to be a promising natural supplement against inflammation and lipid peroxidation and that can significantly enhance overall health. Additionally, the study underscores the necessity for further research to ascertain the optimal dosage, formulation, and duration of supplementation, maximizing the potential health advantages.
Conclusion: This systematic review provides evidence supporting the health benefits associated with palm TRF.
Systematic Review Registration: PROSPERO registration no. CRD42020204070.
(© The Author(s) 2024. Published by Oxford University Press on behalf of the International Life Sciences Institute.)
Databáze: MEDLINE