Multicountry Spread of Influenza A(H1N1)pdm09 Viruses with Reduced Oseltamivir Inhibition, May 2023-February 2024.

Autor: Patel MC, Nguyen HT, Pascua PNQ, Gao R, Steel J, Kondor RJ, Gubareva LV
Jazyk: angličtina
Zdroj: Emerging infectious diseases [Emerg Infect Dis] 2024 Jul; Vol. 30 (7), pp. 1410-1415.
DOI: 10.3201/eid3007.240480
Abstrakt: Since May 2023, a novel combination of neuraminidase mutations, I223V + S247N, has been detected in influenza A(H1N1)pdm09 viruses collected in countries spanning 5 continents, mostly in Europe (67/101). The viruses belong to 2 phylogenetically distinct groups and display ≈13-fold reduced inhibition by oseltamivir while retaining normal susceptibility to other antiviral drugs.
Databáze: MEDLINE