Potential role of CTSS in AMDImmune modulatory and anti-angiogenic effects of cathepsin S knockdown in ARPE-19 cells.
Autor: | Preya UH; Ophthalmology Department, School of Medicine, Chung-Ang University, Dongjak-gu, Seoul, Republic of Korea., Sayed S; Ophthalmology Department, School of Medicine, Chung-Ang University, Dongjak-gu, Seoul, Republic of Korea., Nguyen NL; Ophthalmology Department, School of Medicine, Chung-Ang University, Dongjak-gu, Seoul, Republic of Korea., Kim JT; Ophthalmology Department, School of Medicine, Chung-Ang University, Dongjak-gu, Seoul, Republic of Korea; Chung-Ang University Hospital, Dongjak-gu, Seoul, Republic of Korea. Electronic address: jeetaek@cau.ac.kr. |
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Jazyk: | angličtina |
Zdroj: | Experimental eye research [Exp Eye Res] 2024 Aug; Vol. 245, pp. 109981. Date of Electronic Publication: 2024 Jun 22. |
DOI: | 10.1016/j.exer.2024.109981 |
Abstrakt: | We aimed to determine the role of cathepsin S (CTSS) in modulating oxidative stress-induced immune and inflammatory reactions and angiogenesis in age-related macular degeneration. Human retinal pigment epithelium cells line ARPE-19 (immature) were maintained and treated with H Competing Interests: Declaration of competing interest The authors have no conflicts of interest to declare. (Copyright © 2024 Elsevier Ltd. All rights reserved.) |
Databáze: | MEDLINE |
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