Intracranial Mesenchymal Tumor, FET-CREB Fusion Positive, Evaluated With 18 F-FET and 18 F-FDG PET/CT.

Autor: Engkebølle C; From the Department of Clinical Physiology & Nuclear Medicine., Elisabeth Engelmann B; Department of Oncology, Copenhagen University Hospital Herlev, Herlev, Denmark., Scheie D; Department of Pathology., Fugleholm K; Department of Neurosurgery, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark., Law I; From the Department of Clinical Physiology & Nuclear Medicine.
Jazyk: angličtina
Zdroj: Clinical nuclear medicine [Clin Nucl Med] 2024 Sep 01; Vol. 49 (9), pp. 892-894. Date of Electronic Publication: 2024 Jun 20.
DOI: 10.1097/RLU.0000000000005346
Abstrakt: Abstract: Intracranial mesenchymal tumor, FET-CREB fusion positive, is a newly recognized and rare CNS tumor that occurs primarily in children and young adults. It is regarded as the intracranial variant of angiomatoid fibrous histiocytoma. Extracranial angiomatoid fibrous histiocytomas are typically located in the extremities and usually discernible on a 18 F-FDG PET/CT scanning. We present a 50-year-old man with recurrence of a primary intracranial mesenchymal tumor with equivocal 18 F-FDG PET/CT findings but with subsequent highly increased metabolic activity using 18 F-FET PET/CT confirming tumor recurrence. This case highlights the importance of 18 F-FET PET/CT, as opposed to 18 F-FDG, in the clinical evaluation of this rare intracranial mesenchymal tumor.
Competing Interests: Conflicts of interest and sources of funding: none declared.
(Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.)
Databáze: MEDLINE