Preliminary profile of the gut microbiota from amerindians in the Brazilian amazon experiencing a process of transition to urbanization.

Autor: Alencar RM; Programa de Pós-graduação em Biotecnologia e Recursos Naturais da Amazônia, Universidade do Estado do Amazonas, Manaus, Brazil., Martínez JG; Programa de Pós-graduação em Biotecnologia e Recursos Naturais da Amazônia, Universidade do Estado do Amazonas, Manaus, Brazil. jose.martinez@colmayor.edu.co.; Grupo de investigación Biociencias, Facultad de Ciencias de la Salud, Institución Universitaria Colegio Mayor de Antioquia, Medellín, Colombia. jose.martinez@colmayor.edu.co., Machado VN; Programa de Pós-graduação em Biotecnologia e Recursos Naturais da Amazônia, Universidade do Estado do Amazonas, Manaus, Brazil.; Laboratório de Evolução e Genética Animal, Universidade Federal do Amazonas, Manaus, Brazil., Alzate JF; National Center for Genomic Sequencing, School of Medicine, Universidad de Antioquia, Medellín, Colombia., Ortiz-Ojeda CP; Programa de Pós-graduação em Biotecnologia e Recursos Naturais da Amazônia, Universidade do Estado do Amazonas, Manaus, Brazil.; Universidad Tecnológica del Perú, Lima, Peru., Matias RR; Programa de Pós-graduação em Biotecnologia e Recursos Naturais da Amazônia, Universidade do Estado do Amazonas, Manaus, Brazil., Benzaquem DC; Programa de Pós-graduação em Biotecnologia e Recursos Naturais da Amazônia, Universidade do Estado do Amazonas, Manaus, Brazil., Santos MCF; Programa de Pós-graduação em Biotecnologia e Recursos Naturais da Amazônia, Universidade do Estado do Amazonas, Manaus, Brazil., Assunção EN; Centro de Apoio Multidisciplinar, Universidade Federal do Amazonas, Manaus, Brazil., Lira EC; Centro de Apoio Multidisciplinar, Universidade Federal do Amazonas, Manaus, Brazil., Astolfi-Filho S; Centro de Apoio Multidisciplinar, Universidade Federal do Amazonas, Manaus, Brazil., Hrbek T; Laboratório de Evolução e Genética Animal, Universidade Federal do Amazonas, Manaus, Brazil.; Department of Biology, Trinity University, San Antonio, USA., Farias IP; Laboratório de Evolução e Genética Animal, Universidade Federal do Amazonas, Manaus, Brazil., Fantin C; Programa de Pós-graduação em Biotecnologia e Recursos Naturais da Amazônia, Universidade do Estado do Amazonas, Manaus, Brazil.
Jazyk: angličtina
Zdroj: Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] [Braz J Microbiol] 2024 Sep; Vol. 55 (3), pp. 2345-2354. Date of Electronic Publication: 2024 Jun 24.
DOI: 10.1007/s42770-024-01413-y
Abstrakt: The Yanomami are one of the oldest indigenous tribes in the Amazon and are direct descendants of the first people to colonize South America 12,000 years ago. They are located on the border between Venezuela and Brazil, with the Venezuelan side remaining uncontacted. While they maintain a hunter-gatherer society, they are currently experiencing contact with urbanized populations in Brazil. The human gut microbiota of traditional communities has become the subject of recent studies due to the Westernization of their diet and the introduction of antibiotics and other chemicals, which have affected microbial diversity in indigenous populations, thereby threatening their existence. In this study, we preliminarily characterized the diversity of the gut microbiota of the Yanomami, a hunter-gatherer society from the Amazon, experiencing contact with urbanized populations. Similarly, we compared their diversity with the population in Manaus, Amazonas. A metabarcoding approach of the 16 S rRNA gene was carried out on fecal samples. Differences were found between the two populations, particularly regarding the abundance of genera (e.g., Prevotella and Bacteroides) and the higher values of the phyla Bacteroidetes over Firmicutes, which were significant only in the Yanomami. Some bacteria were found exclusively in the Yanomami (Treponema and Succinivibrio). However, diversity was statistically equal between them. In conclusion, the composition of the Yanomami gut microbiota still maintains the profile characteristic of a community with a traditional lifestyle. However, our results suggest an underlying Westernization process of the Yanomami microbiota when compared with that of Manaus, which must be carefully monitored by authorities, as the loss of diversity can be a sign of growing danger to the health of the Yanomami.
(© 2024. The Author(s).)
Databáze: MEDLINE
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