Clinical Presentation, Tumor Characteristics, and Management of Intradiverticular Transitional Cell Carcinoma of the Urinary Bladder: A Systematic Review.

Autor:	Aijaz P; Internal Medicine, Charleston Area Medical Center, Charleston, USA., Farooqi Baloch K; Internal Medicine, Hofstra University, Hempstead, USA., Faiz H; Internal Medicine, Allama Iqbal Medical College, Lahore, PAK., Durvesh AK; Internal Medicine, Dow University of Health Sciences, Karachi, PAK., Tirmizi SJ; Internal Medicine, Dow University of Health Sciences, Karachi, PAK., Khan M; Internal Medicine, Dow University of Health Sciences, Karachi, PAK., Sohail H; Internal Medicine, Dow University of Health Sciences, Karachi, PAK., Khalid S; Internal Medicine, Dow University of Health Sciences, Karachi, PAK., Niazi MA; Internal Medicine, Dow University of Health Sciences, Karachi, PAK., Kamran A; Hematology and Oncology, Charleston Area Medical Center, Charleston, USA.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2024 Jun 23; Vol. 16 (6), pp. e62974. Date of Electronic Publication: 2024 Jun 23 (Print Publication: 2024).
DOI:	10.7759/cureus.62974
Abstrakt:	Intradiverticular transitional cell carcinoma (TCC) of the bladder poses unique challenges due to its presentation within the bladder diverticula. This review synthesizes current knowledge on the diagnosis and management of this condition, emphasizing the need for early detection to optimize patient outcomes. The literature underscores the importance of tailored treatment strategies, ranging from radical surgeries to adjuvant chemotherapy, to combat the aggressive nature of intradiverticular TCC. Additionally, stringent post-treatment surveillance protocols are vital in addressing high recurrence rates. Future research directions include biomarker identification, comparative efficacy studies of treatment modalities, and the exploration of innovative therapeutic approaches such as immunotherapy. Longitudinal studies analyzing patient outcomes will provide valuable insights into survival rates and quality of life post-treatment, informing future clinical guidelines. This comprehensive review aims to enhance understanding and management strategies for intradiverticular TCC, paving the way for improved patient care and outcomes in this challenging form of bladder cancer. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2024, Aijaz et al.)
Databáze:	MEDLINE
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