First-line treatment for femoroacetabular impingement syndrome and hip-related quality of life: study protocol for a multicentre randomised controlled trial comparing a 6-month supervised strength exercise intervention to usual care (the Better Hip Trial).

Autor:	Foldager FN; Department of Orthopaedic Surgery, Aarhus University Hospital, Aarhus, Denmark Frederikfoldager@clin.au.dk.; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark., Kierkegaard-Brøchner S; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.; Department of Physio and Occupational Therapy and Orthopaedic Surgery, Horsens Regional Hospital, Horsens, Denmark., Kemp JL; La Trobe Sport and Exercise Medicine Research Centre, La Trobe University, Bundoora, Victoria, Australia., van Tulder MW; Department of Human Movement Sciences, Faculty Behavioural & Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam, Netherlands., Lund B; Orthopaedic Surgery, Horsens Regional Hospital, Horsens, Denmark., Mygind-Klavsen B; Department of Orthopaedic Surgery, Aarhus University Hospital, Aarhus, Denmark., Bibby BM; Department of Biostatistics, Aarhus University, Aarhus, Denmark., Dalgas U; Exercise Biology, Department of Public Health, Aarhus University, Aarhus, Denmark., Mechlenburg I; Department of Orthopaedic Surgery, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.; Exercise Biology, Department of Public Health, Aarhus University, Aarhus, Denmark.
Jazyk:	angličtina
Zdroj:	BMJ open [BMJ Open] 2024 Jun 21; Vol. 14 (6), pp. e078726. Date of Electronic Publication: 2024 Jun 21.
DOI:	10.1136/bmjopen-2023-078726
Abstrakt:	Introduction: Femoroacetabular impingement syndrome (FAIS) is a motion-related and position-related clinical condition of the hip associated with pain, reduced physical function and hip-related quality of life (QoL). Interestingly, higher maximal muscle strength is associated with less pain, better physical function and improved QoL in people with FAIS. Furthermore, preliminary evidence suggests that a proportion of patients with FAIS respond positively to strength exercise as first-line treatment. Nonetheless, there is little evidence supporting a specific exercise intervention offered as a first-line treatment. We will conduct a randomised controlled trial investigating the clinical effectiveness and cost-effectiveness of a 6-month strength exercise intervention compared with usual care as first-line treatment in patients with FAIS. Methods and Analysis: This is a multicentre randomised controlled trial that will be conducted at hospitals and physiotherapy clinics across Denmark and Australia. A total of 120 patients with FAIS will be randomised (1:1) to 6 months of supervised strength exercise or usual care. The primary outcome is the change in hip-related QoL measured using the International Hip and Outcome Tool 33 (iHOT-33) from baseline to the end of intervention. A health economic evaluation will be conducted from a societal and healthcare perspective based on the data collection over a 12-month period starting at baseline. The analysis will calculate incremental cost-effectiveness ratios using quality-adjusted life-years and iHOT-33 scores while estimating costs using microcosting and cost questionnaires. Secondary outcomes include objectively measured physical function at baseline and after 6 months and patient-reported outcomes measured at baseline, 3-month, 6-month and 12-month follow-up. Ethics and Dissemination: The trial has been approved by the Committee on Health Research Ethics in the Central Denmark Region (journal no 1-10-72-45-23) and La Trobe University Human Ethics Committee (HEC24042) and is registered at the Central Denmark Region List of Research Projects (journal no 1-16-02-115-23). Informed consent will be obtained from each participant before randomisation. Results will be published in international peer-reviewed scientific journals. Trial Registration Number: NCT05927935. Competing Interests: Competing interests: None declared. (© Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)
Databáze:	MEDLINE
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