Multi-residue determination of biocides in dairy products and slurry feed using QuEChERS extraction and liquid chromatography combined with high resolution mass spectrometry (LC-ESI-QOrbitrap™-MS).

Autor: Dos Santos ID; Wageningen Food Safety Research, part of Wageningen University & Research, Wageningen, the Netherlands; Department of Food Technology and Science, Federal University of Santa Maria, Roraima Avenue 1000, Camobi, Rio Grande do Sul state, Santa Maria 97105-900, RS, Brazil. Electronic address: ingridsduarte@gmail.com., Zomer P; Wageningen Food Safety Research, part of Wageningen University & Research, Wageningen, the Netherlands., Pizzutti IR; Center of Research and Analysis of Contaminants (CEPARC), Department of Chemistry, Roraima Avenue 1000, Camobi, Rio Grande do Sul state, Santa Maria 97105-900, RS, Brazil., Wagner R; Department of Food Technology and Science, Federal University of Santa Maria, Roraima Avenue 1000, Camobi, Rio Grande do Sul state, Santa Maria 97105-900, RS, Brazil., Mol H; Wageningen Food Safety Research, part of Wageningen University & Research, Wageningen, the Netherlands.
Jazyk: angličtina
Zdroj: Food chemistry [Food Chem] 2024 Nov 01; Vol. 457, pp. 140117. Date of Electronic Publication: 2024 Jun 15.
DOI: 10.1016/j.foodchem.2024.140117
Abstrakt: Given that the determination of biocides in food and feed is currently not routinely done, more information on these compounds is useful for consumer's safety. This work describes a sensitive and reliable method for quantitative analysis of a wide range of biocides in dairy products and slurry feed. The method comprises acetate-buffered QuEChERS extraction without clean-up. Analyses were performed by LC-Q-Orbitrap™-MS and a full-scan acquisition event without fragmentation was followed by five fragmentation events (data-independent acquisition-DIA). The quantitative validation was performed according to SANTE/11312/2021 at 10, 50 and 200 ng g -1 spiking levels, and the results showed that the vast majority of the compounds met the criteria for trueness and precision. The LOQ was 10 ng g -1 for the majority of biocides depending on the matrix. The method was successfully applied to quantify biocides in dairy products and feed.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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