The 2024 Pediatric Sepsis Challenge: Predicting In-Hospital Mortality in Children With Suspected Sepsis in Uganda.

Autor:	Huxford C; Institute for Global Health, BC Children's Hospital and BC Women's Hospital + Health Centre, Vancouver, BC, Canada., Rafiei A; Department of Computer Science and Informatics, Emory University, Atlanta, GA., Nguyen V; Institute for Global Health, BC Children's Hospital and BC Women's Hospital + Health Centre, Vancouver, BC, Canada., Wiens MO; Institute for Global Health, BC Children's Hospital and BC Women's Hospital + Health Centre, Vancouver, BC, Canada.; Department of Anesthesia, Pharmacology & Therapeutics, University of British Columbia, Vancouver, BC, Canada.; BC Children's Hospital Research Institute, BC Children's Hospital, Vancouver, BC, Canada., Ansermino JM; Institute for Global Health, BC Children's Hospital and BC Women's Hospital + Health Centre, Vancouver, BC, Canada.; Department of Anesthesia, Pharmacology & Therapeutics, University of British Columbia, Vancouver, BC, Canada.; BC Children's Hospital Research Institute, BC Children's Hospital, Vancouver, BC, Canada., Kissoon N; Institute for Global Health, BC Children's Hospital and BC Women's Hospital + Health Centre, Vancouver, BC, Canada.; BC Children's Hospital Research Institute, BC Children's Hospital, Vancouver, BC, Canada.; Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada., Kumbakumba E; Department of Paediatrics and Child Health, Mbarara University of Science and Technology, Mbarara, Uganda., Businge S; Holy Innocents Children's Hospital, Mbarara, Uganda., Komugisha C; Walimu, Kampala, Uganda., Tayebwa M; Walimu, Kampala, Uganda., Kabakyenga J; Department of Community Health, Mbarara University of Science and Technology, Mbarara, Uganda.; Maternal Newborn and Child Health Institute, Mbarara University of Science and Technology, Mbarara, Uganda., Mugisha NK; Walimu, Kampala, Uganda., Kamaleswaran R; Department of Biomedical Informatics, Emory University School of Medicine, Atlanta, GA.; Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA.
Jazyk:	angličtina
Zdroj:	Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies [Pediatr Crit Care Med] 2024 Jun 21. Date of Electronic Publication: 2024 Jun 21.
DOI:	10.1097/PCC.0000000000003556
Abstrakt:	The aim of this "Technical Note" is to inform the pediatric critical care data research community about the "2024 Pediatric Sepsis Data Challenge." This competition aims to facilitate the development of open-source algorithms to predict in-hospital mortality in Ugandan children with sepsis. The challenge is to first develop an algorithm using a synthetic training dataset, which will then be scored according to standard diagnostic testing criteria, and then be evaluated against a nonsynthetic test dataset. The datasets originate from admissions to six hospitals in Uganda (2017-2020) and include 3837 children, 6 to 60 months old, who were confirmed or suspected to have a diagnosis of sepsis. The synthetic dataset was created from a random subset of the original data. The test validation dataset closely resembles the synthetic dataset. The challenge should generate an optimal model for predicting in-hospital mortality. Following external validation, this model could be used to improve the outcomes for children with proven or suspected sepsis in low- and middle-income settings. Competing Interests: Ms. Huxford’s institution received funding from Grand Challenges Canada, Thrasher Research Fund, BC Children’s Hospital Foundation, and Mining4Life. Dr. Businge received funding from the Pediatric Sepsis Data CoLaboratory, the World Federation of Pediatric Intensive and Critical Care Societies, the University of British Columbia, and the BC Children’s Hospital Foundation. Dr. Komugisha received support for article research from Grand Challenges Canada. Dr. Tayebwa received funding from the Mbarara University of Science and Technology. Dr. Kamaleswaran received support for article research from the National Institutes of Health. The remaining authors have disclosed that they do not have any potential conflicts of interest. (Copyright © 2024 by the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies.)
Databáze:	MEDLINE
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