An Image-Guided Percutaneous Core Needle Biopsy for Accurate Assessment of Musculoskeletal Tumors: A Targeted Diagnosis.

Autor:	Arvind Kumar B; Department of Orthopaedics, Nizam's Institute of Medical Sciences, Hyderabad, IND., Peddamadyam S; Department of Orthopaedics, Nizam's Institute of Medical Sciences, Hyderabad, IND., Krishna V; Department of Orthopaedics, Nizam's Institute of Medical Sciences, Hyderabad, IND., Kancherla NR; Department of Orthopaedics, Nizam's Institute of Medical Sciences, Hyderabad, IND., Nayak KN; Department of Orthopaedic Surgery, Nizam's Institute of Medical Sciences, Hyderabad, IND., Cherukuri N; Department of Orthopaedics, Nizam's Institute of Medical Sciences, Hyderabad, IND., Uppin SG; Department of Pathology and Laboratory Medicine, Nizam's Institute of Medical Sciences, Hyderabad, IND.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2024 May 21; Vol. 16 (5), pp. e60757. Date of Electronic Publication: 2024 May 21 (Print Publication: 2024).
DOI:	10.7759/cureus.60757
Abstrakt:	Background Accurate diagnosis of musculoskeletal tumors is essential for guiding appropriate treatment strategies. Percutaneous core needle biopsy (PCNB) is increasingly recognized as a valuable method for obtaining tissue samples for histopathological examination. This study aims to evaluate the diagnostic accuracy and clinical utility of PCNB in diagnosing musculoskeletal tumors. Methodology A total of 152 cases suspected of musculoskeletal tumors underwent PCNB at our tertiary care center between 2020 and 2023. Pre-biopsy evaluation included comprehensive clinical assessment and imaging studies. Core biopsies were performed under image guidance, with specimens sent for histopathological examination and culture sensitivity analysis. Diagnostic yield, accuracy, and performance metrics of PCNB were assessed. Results PCNB demonstrated a diagnostic yield of 93.4%. However, in cases where initial biopsies were inconclusive, repeat core biopsy or open biopsy provided the necessary diagnostic clarity. PCNB demonstrated a remarkable diagnostic accuracy of 97.9%, with a specificity and positive predictive value of 100%. There were no post-biopsy complications and no instances of local recurrence from the biopsy tract. Conclusions PCNB can be a reliable method for diagnosing musculoskeletal tumors, offering high diagnostic accuracy and minimal complications. The utilization of image guidance enhances precision and reduces the risk of complications. PCNB proves effective in diagnosing both primary tumors and bone infections, facilitating timely and appropriate treatment strategies in orthopedic oncology. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2024, Arvind Kumar et al.)
Databáze:	MEDLINE
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