Lance Adams Syndrome in the Setting of COVID-19 Pneumonia.

Autor:	Krishnaiengar SR; Neurology, University of Florida College of Medicine - Jacksonville, Jacksonville, USA., Cruz-Saavedra L; Neurology, University of Florida College of Medicine - Jacksonville, Jacksonville, USA., Lavu VS; Neurology, University of Florida, Gainesville, USA., Bautista RE; Neurology, University of Florida College of Medicine - Jacksonville, Jacksonville, USA.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2024 May 19; Vol. 16 (5), pp. e60621. Date of Electronic Publication: 2024 May 19 (Print Publication: 2024).
DOI:	10.7759/cureus.60621
Abstrakt:	Lance-Adams syndrome (LAS) is a rare clinical presentation of hypoxic-ischemic brain injury typically occurring in the setting of cardiac arrest. It is rare for it to be associated with respiratory failure. The advent of the COVID-19 pandemic heralded a new cause of respiratory failure, and not much is known about the occurrence of Lance-Adams syndrome in the context of COVID-19 pneumonia. A 23-year-old male was brought to the emergency department (ED) after being found unconscious at home. He had prominent generalized myoclonus in the context of COVID-19 pneumonia and a possible clonazepam overdose. Magnetic resonance imaging (MRI) of the brain with and without contrast revealed findings suggestive of hypoxic-ischemic brain injury. A diagnosis of LAS was made based on electroencephalography (EEG). As LAS typically carries a relatively favorable prognosis, aggressive treatment was pursued. This resulted in a fairly good outcome, although he had to be maintained on several antiseizure medications. Our case is a rare occurrence of Lance-Adams syndrome in the setting of respiratory failure and COVID-19 pneumonia in the absence of cardiac arrest. It is critical to distinguish myoclonic status epilepticus (MSE) from Lance-Adams syndrome due to the difference in prognosis. Our case can provide future direction for studies in a larger cohort of patients to see if LAS is frequently associated with respiratory failure secondary to COVID-19 pneumonia in the absence of cardiac arrest. It is important to consider Lance-Adams syndrome as one of the emerging neurological complications of COVID-19 pneumonia. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2024, Krishnaiengar et al.)
Databáze:	MEDLINE
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