Beliefs, compulsive behavior and reduced confidence in control.

Autor: Rigoux L; Max Planck Institute for Metabolism Research, Cologne, Germany.; Translational Neuromodeling Unit, Institute for Biomedical Engineering, University of Zurich and Swiss Federal Institute of Technology Zurich, Zurich, Switzerland., Stephan KE; Max Planck Institute for Metabolism Research, Cologne, Germany.; Translational Neuromodeling Unit, Institute for Biomedical Engineering, University of Zurich and Swiss Federal Institute of Technology Zurich, Zurich, Switzerland., Petzschner FH; Robert J. and Nancy D. Carney Institute for Brain Science, Brown University, Providence, Rhode Island, United States of America.; Department of Psychiatry and Human Behavior, Brown University, Providence, Rhode Island, United States of America.; Center for Digital Health, Brown University, Providence, Rhode Island, United States of America.
Jazyk: angličtina
Zdroj: PLoS computational biology [PLoS Comput Biol] 2024 Jun 20; Vol. 20 (6), pp. e1012207. Date of Electronic Publication: 2024 Jun 20 (Print Publication: 2024).
DOI: 10.1371/journal.pcbi.1012207
Abstrakt: OCD has been conceptualized as a disorder arising from dysfunctional beliefs, such as overestimating threats or pathological doubts. Yet, how these beliefs lead to compulsions and obsessions remains unclear. Here, we develop a computational model to examine the specific beliefs that trigger and sustain compulsive behavior in a simple symptom-provoking scenario. Our results demonstrate that a single belief disturbance-a lack of confidence in the effectiveness of one's preventive (harm-avoiding) actions-can trigger and maintain compulsions and is directly linked to compulsion severity. This distrust can further explain a number of seemingly unrelated phenomena in OCD, including the role of not-just-right feelings, the link to intolerance to uncertainty, perfectionism, and overestimation of threat, and deficits in reversal and state learning. Our simulations shed new light on which underlying beliefs drive compulsive behavior and highlight the important role of perceived ability to exert control for OCD.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright: © 2024 Rigoux et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)
Databáze: MEDLINE
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