ASXL1/TET2 genotype-based risk stratification outperforms ASXL1 mutational impact and is independent of mutant variant allele fractions in chronic myelomonocytic leukemia.

Autor: Csizmar CM; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN., Gurney M; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN., Kanagal-Shamanna R; Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX., Chien K; Division of Cancer Medicine, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX., Hammond D; Division of Cancer Medicine, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX., Lasho TL; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN., Finke CM; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN., Dean C; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN., Natu A; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN., Mangaonkar AA; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN., Al-Kali A; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN., Gangat N; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN., Tefferi A; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN., Alkhateeb H; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN., Garcia-Manero G; Division of Cancer Medicine, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX., Komrokji RS; Department of Malignant Hematology, H. Lee Moffitt Cancer Center, Tampa, FL., Ali NA; Department of Malignant Hematology, H. Lee Moffitt Cancer Center, Tampa, FL., Padron E; Department of Malignant Hematology, H. Lee Moffitt Cancer Center, Tampa, FL., Montalban-Bravo G; Division of Cancer Medicine, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX., Patnaik MM; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN. patnaik.mrinal@mayo.edu.
Jazyk: angličtina
Zdroj: Haematologica [Haematologica] 2024 Oct 01; Vol. 109 (10), pp. 3419-3425. Date of Electronic Publication: 2024 Oct 01.
DOI: 10.3324/haematol.2024.285410
Databáze: MEDLINE