Autor: |
Song X; National Science Library, Chinese Academy of Sciences, Beijing 100190, China.; Department of Information Resources Management, School of Economics and Management, University of Chinese Academy of Sciences, Beijing 100190, China., Song W; Jiangsu Taizhou People's Hospital, Taizhou 225306, China.; School of Integrative Medicine, Nanjing University of Traditional Chinese Medicine, Nanjing 210023, China., Cui L; College of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China., Duong TQ; Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, NY 10461, USA., Pandy R; Indian Council of Forestry Research & Education, Dehradun 248006, India., Liu H; Centre for Planetary Health and Food Security, School of Environment and Science, Griffith University, Nathan, Brisbane, QLD 4111, Australia., Zhou Q; Department of Library, China Agricultural University (East Campus), 17 Qinghua East Road, Haidian District, Beijing 100193, China., Sun J; Department of Library, China Agricultural University (East Campus), 17 Qinghua East Road, Haidian District, Beijing 100193, China., Liu Y; National Science Library, Chinese Academy of Sciences, Beijing 100190, China.; Department of Information Resources Management, School of Economics and Management, University of Chinese Academy of Sciences, Beijing 100190, China., Li T; School of Agriculture and Food Sustainability, The University of Queensland, St. Lucia, Brisbane, QLD 4072, Australia. |
Abstrakt: |
Background: Long COVID, characterized by a persistent symptom spectrum following SARS-CoV-2 infection, poses significant health, social, and economic challenges. This review aims to consolidate knowledge on its epidemiology, clinical features, and underlying mechanisms to guide global responses; Methods: We conducted a literature review, analyzing peer-reviewed articles and reports to gather comprehensive data on long COVID's epidemiology, symptomatology, and management approaches; Results: Our analysis revealed a wide array of long COVID symptoms and risk factors, with notable demographic variability. The current understanding of its pathophysiology suggests a multifactorial origin yet remains partially understood. Emerging diagnostic criteria and potential therapeutic strategies were identified, highlighting advancements in long COVID management; Conclusions: This review highlights the multifaceted nature of long COVID, revealing a broad spectrum of symptoms, diverse risk factors, and the complex interplay of physiological mechanisms underpinning the condition. Long COVID symptoms and disorders will continue to weigh on healthcare systems in years to come. Addressing long COVID requires a holistic management strategy that integrates clinical care, social support, and policy initiatives. The findings underscore the need for increased international cooperation in research and health planning to address the complex challenges of long COVID. There is a call for continued refinement of diagnostic and treatment modalities, emphasizing a multidisciplinary approach to manage the ongoing and evolving impacts of the condition. |