Effect of Holder Pasteurization, Mode of Delivery, and Infant's Gender on Fatty Acid Composition of Donor Breast Milk.

Autor: Vass RA; Department of Obstetrics and Gynecology, Medical School University of Pécs, 7624 Pécs, Hungary.; National Laboratory on Human Reproduction, University of Pécs, 7624 Pécs, Hungary.; Obstetrics and Gynecology, Magyar Imre Hospital, 8400 Ajka, Hungary., Zhang M; Department of Nutrition, Faculty of Food Science and Technology, Hungarian University of Agriculture and Life Sciences, 1118 Budapest, Hungary., Simon Sarkadi L; Department of Nutrition, Faculty of Food Science and Technology, Hungarian University of Agriculture and Life Sciences, 1118 Budapest, Hungary., Üveges M; Division of Chemical, Noise, Vibration, and Lighting Technology Laboratories, Department of Methodology and Public Health Laboratories, National Center for Public Health and Pharmacy, 1096 Budapest, Hungary., Tormási J; Department of Food Chemistry and Analysis, Faculty of Food Science and Technology, Hungarian University of Agriculture and Life Sciences, 1118 Budapest, Hungary., Benes EL; Department of Food Chemistry and Analysis, Faculty of Food Science and Technology, Hungarian University of Agriculture and Life Sciences, 1118 Budapest, Hungary., Ertl T; Department of Obstetrics and Gynecology, Medical School University of Pécs, 7624 Pécs, Hungary.; National Laboratory on Human Reproduction, University of Pécs, 7624 Pécs, Hungary., Vari SG; International Research and Innovation in Medicine Program, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Jazyk: angličtina
Zdroj: Nutrients [Nutrients] 2024 May 29; Vol. 16 (11). Date of Electronic Publication: 2024 May 29.
DOI: 10.3390/nu16111689
Abstrakt: Breast milk (BM) plays a crucial role in providing essential fatty acids (FA) and energy for the growing infant. When the mother's own BM is not available, nutritional recommendations suggest donor milk (DM) in clinical and home practices. BM was collected from a variety of donor mothers in different lactation stages. Holder pasteurization (HoP) eliminates potential contaminants to ensure safety. FA content of BM samples from the Breast Milk Collection Center of Pécs, Hungary, were analyzed before and after HoP. HoP decreases the level of C6:0, C8:0, C14:1n-5c, C18:1n-9c, C18:3n-6c, C18:3n-3c, and C20:4n-6c in BM, while C14:0, C16:0, C18:1n-9t, C22:0, C22:1n-9c, C24:0, C24:1n-9c, and C22:6n-3c were found in elevated concentration after HoP. We did not detect time-dependent concentration changes in FAs in the first year of lactation. BM produced for girl infants contains higher C20:2n-6c levels. In the BM of mothers who delivered via cesarean section, C12:0, C15:0, C16:0, C17:0, C18:0, C18:1n-9t, C22:1n-9c levels were higher, while C18:2n-6c, C22:0, C24:0, and C22:6n-3c concentrations were lower compared to mothers who gave birth spontaneously. FAs in BM are constant during the first year of lactation. Although HoP modifies the concentration of different FAs, pasteurized DM provides essential FAs to the developing infant. Current data providing information about the FA profile of BM gives origination to supplementation guidelines.
Databáze: MEDLINE