Changes in the epidemiology of kidney replacement therapy across Europe in 2020-the first year of the COVID-19 pandemic: an ERA Registry study.

Autor:	Kramer A; ERA Registry, Department of Medical Informatics Amsterdam UMC location University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Public Health Research Institute, Quality of Care, Amsterdam, The Netherlands., Jager KJ; ERA Registry, Department of Medical Informatics Amsterdam UMC location University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Public Health Research Institute, Quality of Care, Amsterdam, The Netherlands., Chesnaye NC; ERA Registry, Department of Medical Informatics Amsterdam UMC location University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Public Health Research Institute, Quality of Care, Amsterdam, The Netherlands., Kerschbaum J; Austrian Dialysis and Transplant Registry, Department of Internal Medicine IV - Nephrology and Hypertension, Medical University Innsbruck, Innsbruck, Austria., Hommel K; Department of Nephrology, Holbaek Hospital, Holbaek, Denmark., Comas Farnés J; Catalan Renal Registry, Catalan Transplant Organization, Health Department, Generalitat of Catalonia, Barcelona, Spain., Trujillo Alemán S; Health Quality Assessment and Information System Service, Dirección General de Programas Asistenciales, Servicio Canario de la Salud, Las Palmas de Gran Canaria, Spain., Santamaria R; Andalusian Autonomous Transplant Coordination Information System, Seville, Spain.; Nephrology Service, Reina Sofia University Hospital, Cordoba, Spain., Finne P; Department of Nephrology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Hemmelder MH; Department of Internal Medicine, Division of Nephrology, Maastricht University Medical Center, Maastricht, The Netherlands.; CARIM School for Cardiovascular Diseases, University of Maastricht, Maastricht, The Netherlands., Åsberg A; Department of Transplantation Medicine, Oslo University Hospital - Rikshospitalet, Oslo, Norway., Nitsch D; UK Renal Registry, Bristol, UK.; Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK., Ambühl P; Institute of Nephrology, Waid and Triemli City Hospital, Zurich, Switzerland., Sørensen SS; Department of Nephrology P, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark., Sánchez-Alvarez JE; Department of Nephrology, Hospital Universitario de Cabuenẽs, Gijón, Asturias, Spain., Segelmark M; Department of Clinical Sciences, Lund University, Lund, Sweden.; Department of Endocrinology, Nephrology and Rheumatology, Skåne University Hospital, Lund, Sweden., Resic H; Society of Nephrology and Dialysis of Bosnia and Herzegovina, Sarajevo, Bosnia and Herzegovina., Ots-Rosenberg M; Department of Internal Medicine, Tartu University Hospital, Estonia., Radunovic D; Clinical Center of Montenegro, Clinic for Nephrology, Podgorica, Montenegro., Palsson R; Division of Nephrology, Landspitali - The National University Hospital of Iceland, Reykjavik, Iceland.; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland., Santiuste de Pablos C; Murcia Renal Registry, Department of Epidemiology, Murcia Regional Health Council, IMIB-Arrixaca, Murcia, Spain.; CIBER Epidemiología y Salud Pública, Madrid, Spain., Rodríguez Arévalo OL; Registry of Renal Patients of the Valencian Community, General Directorate of Public Health and Addictions, Ministry of Universal Health and Public Health, Valencia, Spain.; Health and Well-being Technologies Program, Polytechnic University of Valencia, Valencia, Spain., Legeai C; Organ and Tissue Procurement and Transplantation Department, Agence de la biomédecine, Saint Denis La Plaine, France., Lausevic M; School of Medicine, University of Belgrade, Belgrade, Serbia.; Clinic of Nephrology, University Clinical Centre of Serbia, Belgrade, Serbia., Bakkaloglu SA; Department of Pediatric Nephrology, Gazi University, Ankara, Turkey., Ortiz A; Department of Nephrology and Hypertension, IIS-Fundacion Jimenez Diaz UAM, Madrid, Spain.; Department of Medicine, Universidad Autonoma de Madrid, Madrid, Spain., Stel VS; ERA Registry, Department of Medical Informatics Amsterdam UMC location University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Public Health Research Institute, Quality of Care, Amsterdam, The Netherlands.
Jazyk:	angličtina
Zdroj:	Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association [Nephrol Dial Transplant] 2024 Oct 30; Vol. 39 (11), pp. 1835-1845.
DOI:	10.1093/ndt/gfae043
Abstrakt:	Background: In 2020, the coronavirus disease 2019 (COVID-19) pandemic caused disruptions in kidney replacement therapy (KRT) services worldwide. The aim of this study was to assess the effect of the COVID-19 pandemic in 2020 on the incidence of KRT, kidney transplantation activity, mortality and prevalence of KRT across Europe. Methods: Patients receiving KRT were included from 17 countries providing data to the European Renal Association Registry. The epidemiology of KRT in 2020 was compared with average data from the period 2017-2019. Changes occurring during the first and second waves of the pandemic were also explored. Results: The incidence of KRT was 6.2% lower in 2020 compared with 2017-2019, with the lowest point (-22.7%) during the first wave in April. The decrease varied across countries, was smaller in males (-5.2%) than in females (-8.2%) and was moderate for peritoneal dialysis (-3.7%) and haemodialysis (-5.4%) but substantial for pre-emptive kidney transplantation (-23.6%). The kidney transplantation rate decreased by 22.5%, reaching a nadir of -80.1% during the first wave, and was greatest for living donor kidney transplants (-30.5%). While in most countries the kidney transplantation rate decreased, in the Nordic/Baltic countries and Greece there was no clear decrease. In dialysis patients, mortality increased by 11.4% and was highest in those 65-74 years of age (16.1%), in those with diabetes as the primary renal disease (15.1%) and in those on haemodialysis (12.4%). In transplant recipients, the mortality was 25.8% higher, but there were no subgroups that stood out. In contrast to the rising prevalence of KRT observed over the past decades across Europe, the prevalence at the end of 2020 (N = 317 787) resembled that of 2019 (N = 317 077). Conclusion: The COVID-19 pandemic has had a substantial impact on the incidence of KRT, kidney transplant activity, mortality of KRT and prevalence of KRT in Europe with variations across countries. (© The Author(s) 2024. Published by Oxford University Press on behalf of the ERA.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu