Sarcanoids A and B, two new lindenane-type sesquiterpenoid dimers from the aerial parts of Sarcandra glabra .

Autor:	Liu J; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, Guangdong, China., Chen QY; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, Guangdong, China., Jin L; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, Guangdong, China., Feng C; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, Guangdong, China., Ma EY; Guangzhou Caizhilin Pharmaceutical Co., Ltd, Guangzhou, Guangdong, China., Xu XJ; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, Guangdong, China., Yang DP; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, Guangdong, China., Zhao ZM; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, Guangdong, China.
Jazyk:	angličtina
Zdroj:	Natural product research [Nat Prod Res] 2024 Jun 17, pp. 1-8. Date of Electronic Publication: 2024 Jun 17.
DOI:	10.1080/14786419.2024.2364919
Abstrakt:	Sarcanoids A and B ( 1 and 2 ), two new lindenane-type sesquiterpenoid dimers with a γ-hydroxysenecioate moiety at C-15', were isolated from the ethyl acetate extract of Sarcandra glabra . The structures were elucidated by extensive analysis of spectroscopic data, and their absolute configurations were determined by single-crystal X-ray crystallography. Compounds 1 and 2 showed moderate inhibitory activities on the nitric oxide (NO) production induced by lipopolysaccharide (LPS) in RAW264.7 macrophages.
Databáze:	MEDLINE
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