Immune-Mediated Necrotizing Myopathy Associated With Anti-signal Recognition Particle Antibody Complicated With Acute Respiratory Distress Syndrome: A Report of Two Cases.

Autor: Fang DW; Neurology, Mackay Memorial Hospital, Taipei City, TWN., Chen YM; Neurology, Mackay Memorial Hospital, Taipei City, TWN.
Jazyk: angličtina
Zdroj: Cureus [Cureus] 2024 May 17; Vol. 16 (5), pp. e60477. Date of Electronic Publication: 2024 May 17 (Print Publication: 2024).
DOI: 10.7759/cureus.60477
Abstrakt: Immune-mediated necrotizing myopathy (IMNM) represents a rare category of inflammatory myopathies characterized by more severe and rapid progression of symmetrical proximal muscle weakness. It is also marked by notably elevated serum muscle enzyme levels and distinct histological features, setting it apart from other types of myositis. Moreover, acute chronic lung respiratory dysfunction is a major comorbidity of great concern. We herein present two cases of IMNM associated with anti-signal recognition particle antibodies complicated by acute respiratory distress syndrome.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright © 2024, Fang et al.)
Databáze: MEDLINE