[Focal cortical dysplasia: visual assessment of MRI and MR morphometry data].

Autor:	Shevchenko AM; Burdenko Neurosurgical Center, Moscow, Russia., Pogosbekyan EL; Burdenko Neurosurgical Center, Moscow, Russia., Batalov AI; Burdenko Neurosurgical Center, Moscow, Russia., Tyurina AN; Burdenko Neurosurgical Center, Moscow, Russia., Fadeeva LM; Burdenko Neurosurgical Center, Moscow, Russia., Agrba SB; Burdenko Neurosurgical Center, Moscow, Russia., Pronin IN; Burdenko Neurosurgical Center, Moscow, Russia.
Jazyk:	ruština
Zdroj:	Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko [Zh Vopr Neirokhir Im N N Burdenko] 2024; Vol. 88 (3), pp. 45-51.
DOI:	10.17116/neiro20248803145
Abstrakt:	Objective: Assessing the diagnostic significance of MR morphometry in determining the localization of focal cortical dysplasias (FCD). Material and Methods: The study included 13 children after surgery for drug-resistant epilepsy caused by FCD type II and stable postoperative remission of seizures (Engel class IA, median follow-up 56 months). We analyzed the results of independent expert assessment of native MR data by three radiologists (HARNESS protocol) and MR morphometry data regarding accuracy of FCD localization. We considered 2 indicators, i.e. local cortical thickening and gray-white matter blurring. Results: FCD detection rate was higher after MR morphometry compared to visual analysis of native MR data using the HARNESS protocol. MR morphometry also makes it possible to more often identify gray-white matter blurring as a sign often missed by radiologists ( p <0.05). Conclusion: MR morphometry is an additional non-invasive method for assessing the localization of FCD.
Databáze:	MEDLINE
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