[Cost-effectiveness and safety of mediastinal transbronchial cryobiopsy guided by endobronchial ultrasonography (CRYO-EBUS) in 110 cases].

Autor: Salcedo Lobera E; Unidad de gestión clínica médico-quirúrgica de enfermedades respiratorias, Hospital Regional Universitario de Málaga, Málaga, España. Electronic address: esalcedolobera@gmail.com., Páez Codeso FM; Unidad de gestión clínica médico-quirúrgica de enfermedades respiratorias, Hospital Regional Universitario de Málaga, Málaga, España., Casado Miranda E; Unidad de gestión clínica médico-quirúrgica de enfermedades respiratorias, Hospital Regional Universitario de Málaga, Málaga, España.
Jazyk: English; Spanish; Castilian
Zdroj: Medicina clinica [Med Clin (Barc)] 2024 Aug 30; Vol. 163 (4), pp. 183-185. Date of Electronic Publication: 2024 Jun 15.
DOI: 10.1016/j.medcli.2024.03.011
Abstrakt: Introduction: Transbronchial needle aspiration guided by endobronchial ultrasonography (EBUSTBNA) has the disadvantage of sometimes offering samples of an unsuitable size for an accurate histo-molecular diagnosis. Transbronchial mediastinal cryobiopsy (CRYOEBUS) is a very novel and additional technique to EBUS-TBNA that allows us to obtain larger and quality samples, improving diagnostic performance.
Material and Methods: Descriptive study of 110 patients with lesions and/or mediastinal lymphadenopathy who underwent EBUS-TBNA and CRYO-EBUS in a single procedure. Our objective was to analyze the diagnostic profitability and safety of the technique.
Results: CRYO-EBUS obtained samples of 0.42cm on average compared to 0.14cm obtained by EBUS-TBNA. The overall diagnostic performance of the techniques was 60% for EBUS-TBNA and 94.5% for CRYO-EBUS. Furthermore, the latter was more sensitive for the diagnosis of both malignant and benign diseases. With a very high security profile.
Conclusions: The CRYO-EBUS technique is cost-effective and safe, and is superior to EBUS-TBNA. Future studies may confirm our findings.
(Copyright © 2024 Elsevier España, S.L.U. All rights reserved.)
Databáze: MEDLINE