Dry immersion rapidly disturbs iron metabolism in men and women: results from the VIVALDI studies.

Autor: Horeau M; INSERM, University of Rennes, INRAE, UMR 1241, AEM2 Platform, Nutrition Metabolisms and Cancer (NuMeCan) institute, Rennes, France.; Laboratory 'Movement Sport and Health Sciences' EA7470, University of Rennes/ENS Rennes, Rennes, France., Navasiolava N; Univ Angers, CRC, CHU Angers, Inserm, CNRS, MITOVASC, Equipe CARME, SFR ICAT, Angers, France., Van Ombergen A; European Space Agency (ESA), Noordwijk, The Netherlands., Custaud MA; Univ Angers, CRC, CHU Angers, Inserm, CNRS, MITOVASC, Equipe CARME, SFR ICAT, Angers, France., Robin A; Univ Angers, CRC, CHU Angers, Inserm, CNRS, MITOVASC, Equipe CARME, SFR ICAT, Angers, France.; Department of Aerospace Engineering, Texas A&M University, College Station, TX, USA., Ropert M; INSERM, University of Rennes, INRAE, UMR 1241, AEM2 Platform, Nutrition Metabolisms and Cancer (NuMeCan) institute, Rennes, France., Antunes I; Telespazio Belgium S.R.L. for the European Space Agency, Noordwijk, The Netherlands., Bareille MP; Institute of Space Physiology and Medicine (MEDES), Toulouse, France., Billette De Villemeur R; Institute of Space Physiology and Medicine (MEDES), Toulouse, France., Gauquelin-Koch G; Centre National d'Etudes Spatiales, Paris, France., Derbré F; Laboratory 'Movement Sport and Health Sciences' EA7470, University of Rennes/ENS Rennes, Rennes, France. frederic.derbre@univ-rennes2.fr., Loréal O; INSERM, University of Rennes, INRAE, UMR 1241, AEM2 Platform, Nutrition Metabolisms and Cancer (NuMeCan) institute, Rennes, France. olivier.loreal@univ-rennes1.fr.
Jazyk: angličtina
Zdroj: NPJ microgravity [NPJ Microgravity] 2024 Jun 15; Vol. 10 (1), pp. 68. Date of Electronic Publication: 2024 Jun 15.
DOI: 10.1038/s41526-024-00399-z
Abstrakt: Iron is essential for cell respiration, muscle metabolism, and oxygen transport. Recent research has shown that simulated microgravity rapidly affects iron metabolism in men. However, its impact on women remains unclear. This study aims to compare iron metabolism alterations in both sexes exposed to 5 days of dry immersion. Our findings demonstrate that women, similarly to men, experience increased systemic iron availability and elevated serum hepcidin levels, indicative of iron misdistribution after short-term exposure to simulated microgravity.
(© 2024. The Author(s).)
Databáze: MEDLINE
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