Biogenesis of bacterial cellulose/xanthan/CeO 2 NPs composite films for active food packaging.

Autor: Mesgari M; Department of Biology, Faculty of Science, Ferdowsi University of Mashhad, Mashhad 9177948974, Iran., Matin MM; Department of Biology, Faculty of Science, Ferdowsi University of Mashhad, Mashhad 9177948974, Iran; Novel Diagnostics and Therapeutics Research Group, Institute of Biotechnology, Ferdowsi University of Mashhad, Mashhad, Iran., Goharshadi EK; Center of Nano Research, Ferdowsi University of Mashhad, Mashhad 9177948974, Iran; Department of Chemistry, Faculty of Science, Ferdowsi University of Mashhad, Mashhad 9177948974, Iran., Mashreghi M; Department of Biology, Faculty of Science, Ferdowsi University of Mashhad, Mashhad 9177948974, Iran; Industrial Biotechnology Research Group, Institute of Biotechnology, Ferdowsi University of Mashhad, Mashhad, Iran; Center of Nano Research, Ferdowsi University of Mashhad, Mashhad 9177948974, Iran. Electronic address: mashrghi@um.ac.ir.
Jazyk: angličtina
Zdroj: International journal of biological macromolecules [Int J Biol Macromol] 2024 Jul; Vol. 273 (Pt 2), pp. 133091. Date of Electronic Publication: 2024 Jun 13.
DOI: 10.1016/j.ijbiomac.2024.133091
Abstrakt: The increasing significance of biopolymer-based food packaging can be attributed to its biodegradability and independence from petroleum-derived materials. Concurrently, metal oxide nanoparticles (NPs) have gained prominence as effective antimicrobial agents against both wild-type and antibiotic-resistant microbes. In this study, cerium oxide or ceria, CeO 2 , nanoparticles with an average diameter of 50 nm were synthesized via a green method utilizing Vibrio sp. VLC cell lysate supernatant. The synthesized CeO 2 NPs displayed remarkable antimicrobial properties, inhibiting the growth of Escherichia coli and Staphylococcus aureus by 93.7 % and 98 %, respectively. To enhance the potential of bacterial cellulose (BC) for advanced applications, we developed a BC/xanthan/CeO 2 nanocomposite using both ex situ and in situ techniques. The integration of CeO 2 NPs within the nanocomposite structure not only improved the inherent properties of BC, but also rendered it suitable for use in active food packaging systems. The nanocomposite exhibited no significant cytotoxicity on the human dermal fibroblast (HDF) cells, confirming its safety. Nanocomposites containing biogenically synthesized CeO 2 NPs demonstrated exceptional efficacy for reducing microbial contamination. Bread samples coated with nanocomposite films displayed no signs of microbial growth. These results support the application of BC/xanthan/CeO 2 nanocomposites as suitable and effective coating materials for antimicrobial food packaging applications.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships, which could have influenced the work reported in this study.
(Copyright © 2024 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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